Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets
(2015) 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 p.1026-1028- Abstract
We present a method to first laterally position microparticles inside droplets by acoustic forces and then split the droplet into three daughter droplets to achieve a 2+fold enrichment of microparticles inside the center droplet. We show that acoustic forces can be applied to both manipulate polystyrene beads (5 μm) and red blood cells inside droplets. The presented technology opens up for development of droplet operations used for medium exchange and particle concentration in droplet-based cell assays.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/d94559d0-77ba-4d09-b44a-518a5d39fb0a
- author
- Fornell, Anna LU ; Jonsson, Håkan N. ; Nilsson, Johan and Tenje, Maria LU
- organization
- publishing date
- 2015
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Droplet microfluidics, Integrated acoustics, Ultrasound
- host publication
- MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- pages
- 3 pages
- publisher
- Chemical and Biological Microsystems Society
- conference name
- 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
- conference location
- Gyeongju, Korea, Republic of
- conference dates
- 2015-10-25 - 2015-10-29
- external identifiers
-
- scopus:84983266550
- ISBN
- 9780979806483
- language
- English
- LU publication?
- yes
- id
- d94559d0-77ba-4d09-b44a-518a5d39fb0a
- date added to LUP
- 2016-12-20 15:05:17
- date last changed
- 2022-01-30 08:43:23
@inproceedings{d94559d0-77ba-4d09-b44a-518a5d39fb0a, abstract = {{<p>We present a method to first laterally position microparticles inside droplets by acoustic forces and then split the droplet into three daughter droplets to achieve a 2+fold enrichment of microparticles inside the center droplet. We show that acoustic forces can be applied to both manipulate polystyrene beads (5 μm) and red blood cells inside droplets. The presented technology opens up for development of droplet operations used for medium exchange and particle concentration in droplet-based cell assays.</p>}}, author = {{Fornell, Anna and Jonsson, Håkan N. and Nilsson, Johan and Tenje, Maria}}, booktitle = {{MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences}}, isbn = {{9780979806483}}, keywords = {{Droplet microfluidics; Integrated acoustics; Ultrasound}}, language = {{eng}}, pages = {{1026--1028}}, publisher = {{Chemical and Biological Microsystems Society}}, title = {{Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets}}, year = {{2015}}, }