Matrix Metalloproteinases - keys to healthier blood vessels in diabetes?
Mulder, Hindrik LU
(2011)
In Journal of Endocrinology
210(1).
p.1-2
- Abstract
- In this issue of J Endocrinol, Schuyler et al. show that intimal lesions in atherosclerosis-prone diabetic apoE-/- mice are reduced by insulin treatment. An increase of metalloproteinase-9 expression was observed in untreated diabetic apoE-/- mice; this was absent in insulin-treated mice. The study suggests that hindering of tissue-remodeling metalloproteinases may account for the beneficial effects of proper metabolic control in patients with diabetes. This clinically relevant finding prompts further exploration.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1973036
- author
- Mulder, Hindrik
LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Endocrinology
- volume
- 210
- issue
- 1
- pages
- 1 - 2
- publisher
- Society for Endocrinology
- external identifiers
-
- wos:000291633800001
- pmid:21555344
- scopus:79960291849
- pmid:21555344
- ISSN
- 1479-6805
- DOI
- 10.1530/JOE-11-0168
- language
- English
- LU publication?
- yes
- id
- da06ea05-cb3b-4eb3-9fd7-fa346c9a7b8d (old id 1973036)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21555344?dopt=Abstract
- date added to LUP
- 2016-04-01 10:06:15
- date last changed
- 2025-04-04 15:13:22
@article{da06ea05-cb3b-4eb3-9fd7-fa346c9a7b8d,
abstract = {{In this issue of J Endocrinol, Schuyler et al. show that intimal lesions in atherosclerosis-prone diabetic apoE-/- mice are reduced by insulin treatment. An increase of metalloproteinase-9 expression was observed in untreated diabetic apoE-/- mice; this was absent in insulin-treated mice. The study suggests that hindering of tissue-remodeling metalloproteinases may account for the beneficial effects of proper metabolic control in patients with diabetes. This clinically relevant finding prompts further exploration.}},
author = {{Mulder, Hindrik}},
issn = {{1479-6805}},
language = {{eng}},
number = {{1}},
pages = {{1--2}},
publisher = {{Society for Endocrinology}},
series = {{Journal of Endocrinology}},
title = {{Matrix Metalloproteinases - keys to healthier blood vessels in diabetes?}},
url = {{http://dx.doi.org/10.1530/JOE-11-0168}},
doi = {{10.1530/JOE-11-0168}},
volume = {{210}},
year = {{2011}},
}