Efficacy and safety of olaparib monotherapy in germline BRCA1/2 mutation carriers with advanced ovarian cancer and three or more lines of prior therapy.
(2016) In Gynecologic Oncology 140(2). p.199-203- Abstract
- The efficacy and safety of olaparib, an oral poly(ADP-ribose) polymerase (PARP) inhibitor, was investigated in a subgroup of patients with germline BRCA1/2 mutated (gBRCA1/2m) advanced ovarian cancer who had received ≥3 prior lines of chemotherapy. Primary data from this Phase II study (Study 42, ClinicalTrials.govNCT01078662) have been reported previously.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8593401
- author
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Gynecologic Oncology
- volume
- 140
- issue
- 2
- pages
- 199 - 203
- publisher
- Academic Press
- external identifiers
-
- pmid:26723501
- scopus:84953204390
- wos:000369678900003
- pmid:26723501
- ISSN
- 1095-6859
- DOI
- 10.1016/j.ygyno.2015.12.020
- language
- English
- LU publication?
- yes
- id
- daa777d4-7791-4af0-8cab-a193c1fe9991 (old id 8593401)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26723501?dopt=Abstract
- date added to LUP
- 2016-04-04 07:23:34
- date last changed
- 2022-04-23 07:57:12
@article{daa777d4-7791-4af0-8cab-a193c1fe9991, abstract = {{The efficacy and safety of olaparib, an oral poly(ADP-ribose) polymerase (PARP) inhibitor, was investigated in a subgroup of patients with germline BRCA1/2 mutated (gBRCA1/2m) advanced ovarian cancer who had received ≥3 prior lines of chemotherapy. Primary data from this Phase II study (Study 42, ClinicalTrials.govNCT01078662) have been reported previously.}}, author = {{Domchek, Susan M and Aghajanian, Carol and Shapira-Frommer, Ronnie and Schmutzler, Rita K and Audeh, M William and Friedlander, Michael and Balmaña, Judith and Mitchell, Gillian and Fried, Georgeta and Stemmer, Salomon M and Hubert, Ayala and Rosengarten, Ora and Loman, Niklas and Robertson, Jane D and Mann, Helen and Kaufman, Bella}}, issn = {{1095-6859}}, language = {{eng}}, number = {{2}}, pages = {{199--203}}, publisher = {{Academic Press}}, series = {{Gynecologic Oncology}}, title = {{Efficacy and safety of olaparib monotherapy in germline BRCA1/2 mutation carriers with advanced ovarian cancer and three or more lines of prior therapy.}}, url = {{http://dx.doi.org/10.1016/j.ygyno.2015.12.020}}, doi = {{10.1016/j.ygyno.2015.12.020}}, volume = {{140}}, year = {{2016}}, }