Advanced

Physical aggression among patients with dementia, neuropathologically confirmed post-mortem

Liljegren, Madeleine LU ; LANDQVIST WALDÖ, MARIA LU and Englund, Elisabet LU (2018) In International Journal of Geriatric Psychiatry 33(2). p.242-248
Abstract
Objective

To investigate the prevalence of physical aggression among patients with dementia of different types and to analyze potential differences in clinical traits, in terms of singular or repetitive behavior and occurrence in early or late stage of the disease. We also aimed at examining against whom the physical aggression was exerted.
Methods

We included 281 cases with a neuropathological dementia diagnosis from the brain bank at the Department of Pathology, Lund University, for this retrospective medical records review. The study covers cases with a post-mortem examination performed between 1967 and 2013.
Results

Of the 281 patients studied, 97 (35%) patients had a history of exerting physical... (More)
Objective

To investigate the prevalence of physical aggression among patients with dementia of different types and to analyze potential differences in clinical traits, in terms of singular or repetitive behavior and occurrence in early or late stage of the disease. We also aimed at examining against whom the physical aggression was exerted.
Methods

We included 281 cases with a neuropathological dementia diagnosis from the brain bank at the Department of Pathology, Lund University, for this retrospective medical records review. The study covers cases with a post-mortem examination performed between 1967 and 2013.
Results

Of the 281 patients studied, 97 (35%) patients had a history of exerting physical aggression during the course of their disease. The patients with frontotemporal dementia exerted physical aggression earlier in the course of their disease than Alzheimer's disease patients. The most frequent victims of the patients' physical aggression were health staff and other patients. The aggression also affected family members as well as (to the demented patient) unknown people. The frequency of the physical aggression differed among the different diagnostic groups; frontotemporal dementia patients exhibiting a higher physical aggression frequency score than did Alzheimer's disease patients.
Conclusions

The patterns of manifested physical aggression thus differ between the frontotemporal dementia and Alzheimer's disease patient groups in this study. Knowledge about such differences may be of value in decision making in patient care. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Journal of Geriatric Psychiatry
volume
33
issue
2
pages
242 - 248
publisher
John Wiley and Sons Ltd
external identifiers
  • scopus:85040727669
ISSN
1099-1166
DOI
10.1002/gps.4777
language
English
LU publication?
yes
id
db0388ec-caf3-4793-941d-e409d824b04f
date added to LUP
2017-09-11 13:50:46
date last changed
2018-02-11 04:31:51
@article{db0388ec-caf3-4793-941d-e409d824b04f,
  abstract     = {Objective<br/><br/>To investigate the prevalence of physical aggression among patients with dementia of different types and to analyze potential differences in clinical traits, in terms of singular or repetitive behavior and occurrence in early or late stage of the disease. We also aimed at examining against whom the physical aggression was exerted.<br/>Methods<br/><br/>We included 281 cases with a neuropathological dementia diagnosis from the brain bank at the Department of Pathology, Lund University, for this retrospective medical records review. The study covers cases with a post-mortem examination performed between 1967 and 2013.<br/>Results<br/><br/>Of the 281 patients studied, 97 (35%) patients had a history of exerting physical aggression during the course of their disease. The patients with frontotemporal dementia exerted physical aggression earlier in the course of their disease than Alzheimer's disease patients. The most frequent victims of the patients' physical aggression were health staff and other patients. The aggression also affected family members as well as (to the demented patient) unknown people. The frequency of the physical aggression differed among the different diagnostic groups; frontotemporal dementia patients exhibiting a higher physical aggression frequency score than did Alzheimer's disease patients.<br/>Conclusions<br/><br/>The patterns of manifested physical aggression thus differ between the frontotemporal dementia and Alzheimer's disease patient groups in this study. Knowledge about such differences may be of value in decision making in patient care.},
  author       = {Liljegren, Madeleine and LANDQVIST WALDÖ, MARIA and Englund, Elisabet},
  issn         = {1099-1166},
  language     = {eng},
  number       = {2},
  pages        = {242--248},
  publisher    = {John Wiley and Sons Ltd},
  series       = {International Journal of Geriatric Psychiatry},
  title        = {Physical aggression among patients with dementia, neuropathologically confirmed post-mortem},
  url          = {http://dx.doi.org/10.1002/gps.4777},
  volume       = {33},
  year         = {2018},
}