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Disassembly of Dipeptide Single Crystals Can Transform the Lipid Membrane into a Network

Fu, Meifang; Li, Qi; Sun, Bingbing; Yang, Yang LU ; Dai, Luru; Nylander, Tommy LU and Li, Junbai (2017) In ACS Nano 11(7). p.7349-7354
Abstract

Coupling between cytoskeleton and membranes is critical to cell movement as well as organelle formation. Here, we demonstrate that self-assembled single crystals of a dipeptide, diphenylalanine (FF), can interact with liposomes to form cytoskeleton-like structures. Under a physiological condition, disassembly of FF crystals deforms and translocates supported lipid membrane. The system exhibits similar dynamic characteristics to the endoplasmic reticulum (ER) network in cells. This bottom-up system thus indicates that external matter can participate in the deformation of liposomes, and disassembly of the nanostructures enables a system with distinct dynamic behaviors.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
biomimetic, membranes, peptides, phospholipids, self-assembly
in
ACS Nano
volume
11
issue
7
pages
6 pages
publisher
The American Chemical Society
external identifiers
  • scopus:85026300151
  • wos:000406649700083
ISSN
1936-0851
DOI
10.1021/acsnano.7b03468
language
English
LU publication?
yes
id
dd298d28-8a4f-49c9-9159-4a999a29f248
date added to LUP
2017-08-31 13:12:53
date last changed
2018-05-06 04:36:22
@article{dd298d28-8a4f-49c9-9159-4a999a29f248,
  abstract     = {<p>Coupling between cytoskeleton and membranes is critical to cell movement as well as organelle formation. Here, we demonstrate that self-assembled single crystals of a dipeptide, diphenylalanine (FF), can interact with liposomes to form cytoskeleton-like structures. Under a physiological condition, disassembly of FF crystals deforms and translocates supported lipid membrane. The system exhibits similar dynamic characteristics to the endoplasmic reticulum (ER) network in cells. This bottom-up system thus indicates that external matter can participate in the deformation of liposomes, and disassembly of the nanostructures enables a system with distinct dynamic behaviors.</p>},
  author       = {Fu, Meifang and Li, Qi and Sun, Bingbing and Yang, Yang and Dai, Luru and Nylander, Tommy and Li, Junbai},
  issn         = {1936-0851},
  keyword      = {biomimetic,membranes,peptides,phospholipids,self-assembly},
  language     = {eng},
  month        = {07},
  number       = {7},
  pages        = {7349--7354},
  publisher    = {The American Chemical Society},
  series       = {ACS Nano},
  title        = {Disassembly of Dipeptide Single Crystals Can Transform the Lipid Membrane into a Network},
  url          = {http://dx.doi.org/10.1021/acsnano.7b03468},
  volume       = {11},
  year         = {2017},
}