Natural history of patients with unoperated atherosclerotic carotid artery disease--results from a retrospective study
(1993) In European Journal of Vascular Surgery 7(2). p.166-170- Abstract
- The natural history of carotid artery disease was studied in a retrospective study of 609 angiograms performed during 1969-1979 on patients who had subsequently not been operated on. The indication for angiography differed, but was aimed at clarifying suspected cerebrovascular events. 578 patients could be followed-up after a median time of 10.4 years (0-22). The median survival time after angiography was 9.7 years for the 355 men and 12.8 years for the 223 women (p = 0.0099). Internal carotid stenosis of > 50% was seen in 9.0% (bilaterally in 2.2%), a stenosis > 75% in 4.5% (bilaterally in 0.9%) and occlusion in 9% (bilaterally in 0.7%). Ulceration was present in 10.7% (bilaterally in 1.6%). 26.5% of the patients had a... (More)
- The natural history of carotid artery disease was studied in a retrospective study of 609 angiograms performed during 1969-1979 on patients who had subsequently not been operated on. The indication for angiography differed, but was aimed at clarifying suspected cerebrovascular events. 578 patients could be followed-up after a median time of 10.4 years (0-22). The median survival time after angiography was 9.7 years for the 355 men and 12.8 years for the 223 women (p = 0.0099). Internal carotid stenosis of > 50% was seen in 9.0% (bilaterally in 2.2%), a stenosis > 75% in 4.5% (bilaterally in 0.9%) and occlusion in 9% (bilaterally in 0.7%). Ulceration was present in 10.7% (bilaterally in 1.6%). 26.5% of the patients had a cerebrovascular event during follow-up, of which 31.4% had transient ischaemic attack or amaurosis fugax. Survival was not influenced by the degree of stenosis, but presence of arteriosclerotic carotid artery disease significantly reduced the median survival time from 11 to 3 years. The main cause of death for men was myocardial infarction (27.7%) and for women a cerebrovascular event (27.8%), a significant difference. From this study, in selected patients it can be concluded that the annual frequency of cerebrovascular events was low, approaching frequencies reported in asymptomatic patients. The cause of death differed between men and women, with more cardiac deaths among men and more cerebrovascular deaths among women. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1107299
- author
- Mätzsch, Thomas LU ; Bergqvist, David ; Lindh, Mats LU ; Maly, Pavel LU and Takolander, Rabbe
- organization
- publishing date
- 1993
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Carotid artery stenosis, Carotid endarterectomy
- in
- European Journal of Vascular Surgery
- volume
- 7
- issue
- 2
- pages
- 166 - 170
- publisher
- Elsevier
- external identifiers
-
- pmid:8462705
- scopus:0027233640
- ISSN
- 0950-821X
- DOI
- 10.1016/S0950-821X(05)80757-1
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Medical Radiology Unit (013241410), Emergency medicine/Medicine/Surgery (013240200)
- id
- df80ed40-cfc3-4bf1-8cd4-a7e9b8b66c2e (old id 1107299)
- date added to LUP
- 2016-04-01 16:35:57
- date last changed
- 2021-01-03 09:11:45
@article{df80ed40-cfc3-4bf1-8cd4-a7e9b8b66c2e,
abstract = {{The natural history of carotid artery disease was studied in a retrospective study of 609 angiograms performed during 1969-1979 on patients who had subsequently not been operated on. The indication for angiography differed, but was aimed at clarifying suspected cerebrovascular events. 578 patients could be followed-up after a median time of 10.4 years (0-22). The median survival time after angiography was 9.7 years for the 355 men and 12.8 years for the 223 women (p = 0.0099). Internal carotid stenosis of > 50% was seen in 9.0% (bilaterally in 2.2%), a stenosis > 75% in 4.5% (bilaterally in 0.9%) and occlusion in 9% (bilaterally in 0.7%). Ulceration was present in 10.7% (bilaterally in 1.6%). 26.5% of the patients had a cerebrovascular event during follow-up, of which 31.4% had transient ischaemic attack or amaurosis fugax. Survival was not influenced by the degree of stenosis, but presence of arteriosclerotic carotid artery disease significantly reduced the median survival time from 11 to 3 years. The main cause of death for men was myocardial infarction (27.7%) and for women a cerebrovascular event (27.8%), a significant difference. From this study, in selected patients it can be concluded that the annual frequency of cerebrovascular events was low, approaching frequencies reported in asymptomatic patients. The cause of death differed between men and women, with more cardiac deaths among men and more cerebrovascular deaths among women.}},
author = {{Mätzsch, Thomas and Bergqvist, David and Lindh, Mats and Maly, Pavel and Takolander, Rabbe}},
issn = {{0950-821X}},
keywords = {{Carotid artery stenosis; Carotid endarterectomy}},
language = {{eng}},
number = {{2}},
pages = {{166--170}},
publisher = {{Elsevier}},
series = {{European Journal of Vascular Surgery}},
title = {{Natural history of patients with unoperated atherosclerotic carotid artery disease--results from a retrospective study}},
url = {{http://dx.doi.org/10.1016/S0950-821X(05)80757-1}},
doi = {{10.1016/S0950-821X(05)80757-1}},
volume = {{7}},
year = {{1993}},
}