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Current indications for surgical treatment of primary hyperparathyroidism in the elderly

Polistena, Andrea LU ; Lucchini, Roberta ; Monacelli, Massimo ; Triola, Roberta ; Avenia, Stefano ; Barillaro, Ivan ; Johnson, Louis Banka LU ; Sanguinetti, Alessandro and Avenia, Nicola (2017) In American Surgeon 83(3). p.296-302
Abstract

This study presents the results of surgery in the elderly for primary hyperparathyroidism (PHPT) from a single institution's experience. We retrospectively analyzed 898 cases of surgically treated PHPT, divided into two groups: 135 elderly patients (A) and 763 patients younger than 65 years (B). PHPT was symptomatic in 68.8 per cent patients in group A and in 81.6 per cent in group B. Unilateral temporary recurrent laryngeal nerve palsy was observed in 0.9 per cent in group A and 0.1 per cent in group B (P > 0.05). No cervical hematomas, mortality or major cardiovascular, neurological, respiratory or metabolic postoperative complications were registered. All the patients evaluated at one year had improvement in the quality of life,... (More)

This study presents the results of surgery in the elderly for primary hyperparathyroidism (PHPT) from a single institution's experience. We retrospectively analyzed 898 cases of surgically treated PHPT, divided into two groups: 135 elderly patients (A) and 763 patients younger than 65 years (B). PHPT was symptomatic in 68.8 per cent patients in group A and in 81.6 per cent in group B. Unilateral temporary recurrent laryngeal nerve palsy was observed in 0.9 per cent in group A and 0.1 per cent in group B (P > 0.05). No cervical hematomas, mortality or major cardiovascular, neurological, respiratory or metabolic postoperative complications were registered. All the patients evaluated at one year had improvement in the quality of life, with increase of bone mineral density (BMD) in 85.6 per cent and 79.8 per cent of patients in groups A and B, with no significant differences between symptomatic and asymptomatic patients. Parathyroidectomy in elderly PHPT patients is safe, with rate of morbidity similar to what observed in younger individuals. Further investigations are recommended to confirm the role of surgery as an effective approach in elderly PHPT patients.

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; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Surgeon
volume
83
issue
3
pages
7 pages
publisher
Southeastern Surgical Congress
external identifiers
  • scopus:85021389174
  • pmid:28316315
ISSN
0003-1348
language
English
LU publication?
yes
id
e3ce753d-93de-4e11-b76c-f4ba89e132a6
alternative location
http://www.ingentaconnect.com/content/sesc/tas/2017/00000083/00000003/art00026;jsessionid=3juq0o68fcdm.x-ic-live-01#expand/collapse
date added to LUP
2018-10-22 13:01:57
date last changed
2024-04-15 14:48:44
@article{e3ce753d-93de-4e11-b76c-f4ba89e132a6,
  abstract     = {{<p>This study presents the results of surgery in the elderly for primary hyperparathyroidism (PHPT) from a single institution's experience. We retrospectively analyzed 898 cases of surgically treated PHPT, divided into two groups: 135 elderly patients (A) and 763 patients younger than 65 years (B). PHPT was symptomatic in 68.8 per cent patients in group A and in 81.6 per cent in group B. Unilateral temporary recurrent laryngeal nerve palsy was observed in 0.9 per cent in group A and 0.1 per cent in group B (P &gt; 0.05). No cervical hematomas, mortality or major cardiovascular, neurological, respiratory or metabolic postoperative complications were registered. All the patients evaluated at one year had improvement in the quality of life, with increase of bone mineral density (BMD) in 85.6 per cent and 79.8 per cent of patients in groups A and B, with no significant differences between symptomatic and asymptomatic patients. Parathyroidectomy in elderly PHPT patients is safe, with rate of morbidity similar to what observed in younger individuals. Further investigations are recommended to confirm the role of surgery as an effective approach in elderly PHPT patients.</p>}},
  author       = {{Polistena, Andrea and Lucchini, Roberta and Monacelli, Massimo and Triola, Roberta and Avenia, Stefano and Barillaro, Ivan and Johnson, Louis Banka and Sanguinetti, Alessandro and Avenia, Nicola}},
  issn         = {{0003-1348}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{296--302}},
  publisher    = {{Southeastern Surgical Congress}},
  series       = {{American Surgeon}},
  title        = {{Current indications for surgical treatment of primary hyperparathyroidism in the elderly}},
  url          = {{http://www.ingentaconnect.com/content/sesc/tas/2017/00000083/00000003/art00026;jsessionid=3juq0o68fcdm.x-ic-live-01#expand/collapse}},
  volume       = {{83}},
  year         = {{2017}},
}