Acoustofluidic platforms for particle manipulation
(2022) In Electrophoresis 43(44750). p.804-818- Abstract
There is an increasing interest in acoustics for microfluidic applications. This field, commonly known as acoustofluidics involves the interaction of ultrasonic standing waves with fluids and dispersed microparticles. The combination of microfluidics and the so-called acoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation where it is possible to move and spatially localize these particles based on the different acoustophysical properties. While it was initially suggested that the acoustic forces could be harmful to the cells and could impact cell viability, proliferation, or function via phenotypic or even genotypic changes, further studies disproved such... (More)
There is an increasing interest in acoustics for microfluidic applications. This field, commonly known as acoustofluidics involves the interaction of ultrasonic standing waves with fluids and dispersed microparticles. The combination of microfluidics and the so-called acoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation where it is possible to move and spatially localize these particles based on the different acoustophysical properties. While it was initially suggested that the acoustic forces could be harmful to the cells and could impact cell viability, proliferation, or function via phenotypic or even genotypic changes, further studies disproved such claims. This review is summarizing some interesting applications of acoustofluidics in the manipulations of biomaterials, such as cells or subcellular vesicles, in works published mainly within the last 5 years.
(Less)
- author
- Novotny, Jakub LU ; Lenshof, Andreas LU and Laurell, Thomas LU
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Acoustics, Acoustofluidics, Cell manipulation, Microfluidics
- in
- Electrophoresis
- volume
- 43
- issue
- 44750
- pages
- 804 - 818
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:85118839149
- pmid:34719049
- ISSN
- 0173-0835
- DOI
- 10.1002/elps.202100291
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2021 Wiley-VCH GmbH
- id
- e44209cf-4c5e-4594-b25f-41d04e2b0ece
- date added to LUP
- 2021-12-02 15:25:44
- date last changed
- 2024-09-08 06:01:52
@article{e44209cf-4c5e-4594-b25f-41d04e2b0ece, abstract = {{<p>There is an increasing interest in acoustics for microfluidic applications. This field, commonly known as acoustofluidics involves the interaction of ultrasonic standing waves with fluids and dispersed microparticles. The combination of microfluidics and the so-called acoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation where it is possible to move and spatially localize these particles based on the different acoustophysical properties. While it was initially suggested that the acoustic forces could be harmful to the cells and could impact cell viability, proliferation, or function via phenotypic or even genotypic changes, further studies disproved such claims. This review is summarizing some interesting applications of acoustofluidics in the manipulations of biomaterials, such as cells or subcellular vesicles, in works published mainly within the last 5 years.</p>}}, author = {{Novotny, Jakub and Lenshof, Andreas and Laurell, Thomas}}, issn = {{0173-0835}}, keywords = {{Acoustics; Acoustofluidics; Cell manipulation; Microfluidics}}, language = {{eng}}, number = {{44750}}, pages = {{804--818}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Electrophoresis}}, title = {{Acoustofluidic platforms for particle manipulation}}, url = {{http://dx.doi.org/10.1002/elps.202100291}}, doi = {{10.1002/elps.202100291}}, volume = {{43}}, year = {{2022}}, }