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Acoustofluidic platforms for particle manipulation

Novotny, Jakub LU orcid ; Lenshof, Andreas LU and Laurell, Thomas LU (2022) In Electrophoresis 43(44750). p.804-818
Abstract

There is an increasing interest in acoustics for microfluidic applications. This field, commonly known as acoustofluidics involves the interaction of ultrasonic standing waves with fluids and dispersed microparticles. The combination of microfluidics and the so-called acoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation where it is possible to move and spatially localize these particles based on the different acoustophysical properties. While it was initially suggested that the acoustic forces could be harmful to the cells and could impact cell viability, proliferation, or function via phenotypic or even genotypic changes, further studies disproved such... (More)

There is an increasing interest in acoustics for microfluidic applications. This field, commonly known as acoustofluidics involves the interaction of ultrasonic standing waves with fluids and dispersed microparticles. The combination of microfluidics and the so-called acoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation where it is possible to move and spatially localize these particles based on the different acoustophysical properties. While it was initially suggested that the acoustic forces could be harmful to the cells and could impact cell viability, proliferation, or function via phenotypic or even genotypic changes, further studies disproved such claims. This review is summarizing some interesting applications of acoustofluidics in the manipulations of biomaterials, such as cells or subcellular vesicles, in works published mainly within the last 5 years.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Acoustics, Acoustofluidics, Cell manipulation, Microfluidics
in
Electrophoresis
volume
43
issue
44750
pages
804 - 818
publisher
John Wiley & Sons Inc.
external identifiers
  • scopus:85118839149
  • pmid:34719049
ISSN
0173-0835
DOI
10.1002/elps.202100291
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2021 Wiley-VCH GmbH
id
e44209cf-4c5e-4594-b25f-41d04e2b0ece
date added to LUP
2021-12-02 15:25:44
date last changed
2024-06-15 22:00:31
@article{e44209cf-4c5e-4594-b25f-41d04e2b0ece,
  abstract     = {{<p>There is an increasing interest in acoustics for microfluidic applications. This field, commonly known as acoustofluidics involves the interaction of ultrasonic standing waves with fluids and dispersed microparticles. The combination of microfluidics and the so-called acoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation where it is possible to move and spatially localize these particles based on the different acoustophysical properties. While it was initially suggested that the acoustic forces could be harmful to the cells and could impact cell viability, proliferation, or function via phenotypic or even genotypic changes, further studies disproved such claims. This review is summarizing some interesting applications of acoustofluidics in the manipulations of biomaterials, such as cells or subcellular vesicles, in works published mainly within the last 5 years.</p>}},
  author       = {{Novotny, Jakub and Lenshof, Andreas and Laurell, Thomas}},
  issn         = {{0173-0835}},
  keywords     = {{Acoustics; Acoustofluidics; Cell manipulation; Microfluidics}},
  language     = {{eng}},
  number       = {{44750}},
  pages        = {{804--818}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Electrophoresis}},
  title        = {{Acoustofluidic platforms for particle manipulation}},
  url          = {{http://dx.doi.org/10.1002/elps.202100291}},
  doi          = {{10.1002/elps.202100291}},
  volume       = {{43}},
  year         = {{2022}},
}