Participant Experiences in the Environmental Determinants of Diabetes in the Young Study: Common Reasons for Withdrawing.
(2016) In Journal of Diabetes Research 2016.- Abstract
- Background. To characterize participant reasons for withdrawing from a diabetes focused longitudinal clinical observational trial (TEDDY) during the first three study years. Methods. 8677 children were recruited into the TEDDY study. At participant withdrawal staff recorded any reason parents provided for withdrawal. Reasons were categorized into (1) family characteristics and (2) protocol reasons. Families who informed staff of their withdrawal were classified as active withdrawals (AW); families without a final contact were considered passive withdrawals (PW). Results. Withdrawal was highest during the first study year (n = 1220). Most families were AW (n = 1549; 73.4%). PW was more common in the United States (n = 1001; 37.8%) and among... (More)
- Background. To characterize participant reasons for withdrawing from a diabetes focused longitudinal clinical observational trial (TEDDY) during the first three study years. Methods. 8677 children were recruited into the TEDDY study. At participant withdrawal staff recorded any reason parents provided for withdrawal. Reasons were categorized into (1) family characteristics and (2) protocol reasons. Families who informed staff of their withdrawal were classified as active withdrawals (AW); families without a final contact were considered passive withdrawals (PW). Results. Withdrawal was highest during the first study year (n = 1220). Most families were AW (n = 1549; 73.4%). PW was more common in the United States (n = 1001; 37.8%) and among young mothers (p = 0.001). The most frequent protocol characteristic was blood draw (55%) and the most common family reason was not having enough time (66%). The blood draw was more common among female participants; being too busy was more common among males. Both reasons were associated with study satisfaction. Conclusions. Results suggest that, for families of children genetically at risk for diabetes, procedures that can be painful/frightening should be used with caution. Study procedures must also be considered for the demands placed on participants. Study satisfaction should be regularly assessed as an indicator of risk for withdrawal. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8504312
- author
- Lernmark, Barbro LU ; Lynch, Kristian ; Baxter, Judith ; Roth, Roswith ; Simell, Tuula ; Smith, Laura ; Swartling, Ulrica LU ; Johnson, Suzanne Bennett and Teddy Study Group, NN
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Diabetes Research
- volume
- 2016
- article number
- 2720650
- publisher
- Hindawi Limited
- external identifiers
-
- pmid:26682228
- scopus:84949255927
- wos:000370250700001
- pmid:26682228
- ISSN
- 2314-6753
- DOI
- 10.1155/2016/2720650
- language
- English
- LU publication?
- yes
- id
- e49577af-0b78-4114-abcb-3f70a180cfb8 (old id 8504312)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26682228?dopt=Abstract
- date added to LUP
- 2016-04-04 07:33:36
- date last changed
- 2022-02-13 05:06:00
@article{e49577af-0b78-4114-abcb-3f70a180cfb8,
abstract = {{Background. To characterize participant reasons for withdrawing from a diabetes focused longitudinal clinical observational trial (TEDDY) during the first three study years. Methods. 8677 children were recruited into the TEDDY study. At participant withdrawal staff recorded any reason parents provided for withdrawal. Reasons were categorized into (1) family characteristics and (2) protocol reasons. Families who informed staff of their withdrawal were classified as active withdrawals (AW); families without a final contact were considered passive withdrawals (PW). Results. Withdrawal was highest during the first study year (n = 1220). Most families were AW (n = 1549; 73.4%). PW was more common in the United States (n = 1001; 37.8%) and among young mothers (p = 0.001). The most frequent protocol characteristic was blood draw (55%) and the most common family reason was not having enough time (66%). The blood draw was more common among female participants; being too busy was more common among males. Both reasons were associated with study satisfaction. Conclusions. Results suggest that, for families of children genetically at risk for diabetes, procedures that can be painful/frightening should be used with caution. Study procedures must also be considered for the demands placed on participants. Study satisfaction should be regularly assessed as an indicator of risk for withdrawal.}},
author = {{Lernmark, Barbro and Lynch, Kristian and Baxter, Judith and Roth, Roswith and Simell, Tuula and Smith, Laura and Swartling, Ulrica and Johnson, Suzanne Bennett and Teddy Study Group, NN}},
issn = {{2314-6753}},
language = {{eng}},
publisher = {{Hindawi Limited}},
series = {{Journal of Diabetes Research}},
title = {{Participant Experiences in the Environmental Determinants of Diabetes in the Young Study: Common Reasons for Withdrawing.}},
url = {{http://dx.doi.org/10.1155/2016/2720650}},
doi = {{10.1155/2016/2720650}},
volume = {{2016}},
year = {{2016}},
}