Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

The role of diagnostic tissue in research

Cheung, Carol C. ; Torlakovic, Emina E. and Porwit, Anna LU (2014) In Pathobiology 81. p.298-303
Abstract

There are two broad classes (or categories) of excised human tissue: diagnostic tissue (DT) and research tissue (RT). Classification of excised human tissue does not define its ultimate use and ultimate use of excised human tissue does not define its classification. While both DT and RT can be used for research, DT has specific requirements with respect to how it must be handled if and when being accessed for research. We highlight distinguishing features of DT: (1) it is a clinical record, (2) it must be identifiable to a specific individual, (3) it is stewarded by pathology departments/clinical laboratories and (4) it has a mandatory retention period. We discuss how the further sub-classification of DT into archived DT (aDT) and... (More)

There are two broad classes (or categories) of excised human tissue: diagnostic tissue (DT) and research tissue (RT). Classification of excised human tissue does not define its ultimate use and ultimate use of excised human tissue does not define its classification. While both DT and RT can be used for research, DT has specific requirements with respect to how it must be handled if and when being accessed for research. We highlight distinguishing features of DT: (1) it is a clinical record, (2) it must be identifiable to a specific individual, (3) it is stewarded by pathology departments/clinical laboratories and (4) it has a mandatory retention period. We discuss how the further sub-classification of DT into archived DT (aDT) and excess DT (eDT) impacts the nature of its role in research. We examine the concept of DT as a clinical record and emphasize the impact of mandatory retention as it applies to how DT may be accessed for research purposes. We explain the role of post-retention eDT as a source of RT as well as procedures for access to in-retention aDT for research. Clarity of such issues will facilitate responsible access to DT for research.

(Less)
Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Access to diagnostic tissue, Biobanking, Diagnostic tissue, Pathology, Research, Residual tissue
in
Pathobiology
volume
81
pages
6 pages
publisher
Karger
external identifiers
  • pmid:25792218
  • scopus:84925345268
ISSN
1015-2008
DOI
10.1159/000362648
language
English
LU publication?
no
id
e60bc9f6-3e31-4302-a25d-10707caa8546
date added to LUP
2019-05-22 09:45:57
date last changed
2024-01-01 06:38:24
@article{e60bc9f6-3e31-4302-a25d-10707caa8546,
  abstract     = {{<p>There are two broad classes (or categories) of excised human tissue: diagnostic tissue (DT) and research tissue (RT). Classification of excised human tissue does not define its ultimate use and ultimate use of excised human tissue does not define its classification. While both DT and RT can be used for research, DT has specific requirements with respect to how it must be handled if and when being accessed for research. We highlight distinguishing features of DT: (1) it is a clinical record, (2) it must be identifiable to a specific individual, (3) it is stewarded by pathology departments/clinical laboratories and (4) it has a mandatory retention period. We discuss how the further sub-classification of DT into archived DT (aDT) and excess DT (eDT) impacts the nature of its role in research. We examine the concept of DT as a clinical record and emphasize the impact of mandatory retention as it applies to how DT may be accessed for research purposes. We explain the role of post-retention eDT as a source of RT as well as procedures for access to in-retention aDT for research. Clarity of such issues will facilitate responsible access to DT for research.</p>}},
  author       = {{Cheung, Carol C. and Torlakovic, Emina E. and Porwit, Anna}},
  issn         = {{1015-2008}},
  keywords     = {{Access to diagnostic tissue; Biobanking; Diagnostic tissue; Pathology; Research; Residual tissue}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{298--303}},
  publisher    = {{Karger}},
  series       = {{Pathobiology}},
  title        = {{The role of diagnostic tissue in research}},
  url          = {{http://dx.doi.org/10.1159/000362648}},
  doi          = {{10.1159/000362648}},
  volume       = {{81}},
  year         = {{2014}},
}