Polyphenolic Constituents and Antioxidant Potential of Geranium stepporum Davis
(2011) In Records of Natural Products 5(1). p.22-28- Abstract
- The crude MeOH extract prepared from the aerial parts of G. stepporum and its EtOAc, n-BuOH, H2O subextracts were screened for their inhibitory activity on H2O2-induced lipid peroxidation in human red blood cells. The EtOAc subextract was found to be the most active one and its chemical composition was further analysed. Six polyphenolic secondary metabolites including quercetin (1), rutin (2), methyl gallate (3), pusilagin (4), 1,3,6-tri-O-galloyl-beta-glucospyranose (5) and 1,2,3,4,6-penta-O-galloyl-beta-glucopyranose (6) were isolated from the EtOAc extract by successive chromatographic methods (Sephadex CC, silica gel CC and P-TLC). The structures of the isolates were elucidated by 1D- and 2D-NMR and MS. This is the first report of... (More)
- The crude MeOH extract prepared from the aerial parts of G. stepporum and its EtOAc, n-BuOH, H2O subextracts were screened for their inhibitory activity on H2O2-induced lipid peroxidation in human red blood cells. The EtOAc subextract was found to be the most active one and its chemical composition was further analysed. Six polyphenolic secondary metabolites including quercetin (1), rutin (2), methyl gallate (3), pusilagin (4), 1,3,6-tri-O-galloyl-beta-glucospyranose (5) and 1,2,3,4,6-penta-O-galloyl-beta-glucopyranose (6) were isolated from the EtOAc extract by successive chromatographic methods (Sephadex CC, silica gel CC and P-TLC). The structures of the isolates were elucidated by 1D- and 2D-NMR and MS. This is the first report of occurrence of hydrolysable tannins in G. stepporum. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1791066
- author
- Sohretoglu, Didem ; Sakar, Mahmut Koray ; Sabuncuoglu, Suna Atasayar ; Ozgunes, Hilal and Sterner, Olov LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Geranium stepporum, Geraniaceae, galloylglucopyranose, hydrolysable, tannin, flavonoid, antioxidant effect
- in
- Records of Natural Products
- volume
- 5
- issue
- 1
- pages
- 22 - 28
- publisher
- ACG Publications
- external identifiers
-
- wos:000285645600003
- scopus:79251587796
- ISSN
- 1307-6167
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
- id
- eba78926-f37d-48fe-8f6c-42b60e047df6 (old id 1791066)
- alternative location
- http://acgpubs.org/RNP/2011/Volume%205/Issue%201/3-RNP-1005-229.pdf
- date added to LUP
- 2016-04-01 13:13:31
- date last changed
- 2022-01-27 18:02:05
@article{eba78926-f37d-48fe-8f6c-42b60e047df6, abstract = {{The crude MeOH extract prepared from the aerial parts of G. stepporum and its EtOAc, n-BuOH, H2O subextracts were screened for their inhibitory activity on H2O2-induced lipid peroxidation in human red blood cells. The EtOAc subextract was found to be the most active one and its chemical composition was further analysed. Six polyphenolic secondary metabolites including quercetin (1), rutin (2), methyl gallate (3), pusilagin (4), 1,3,6-tri-O-galloyl-beta-glucospyranose (5) and 1,2,3,4,6-penta-O-galloyl-beta-glucopyranose (6) were isolated from the EtOAc extract by successive chromatographic methods (Sephadex CC, silica gel CC and P-TLC). The structures of the isolates were elucidated by 1D- and 2D-NMR and MS. This is the first report of occurrence of hydrolysable tannins in G. stepporum.}}, author = {{Sohretoglu, Didem and Sakar, Mahmut Koray and Sabuncuoglu, Suna Atasayar and Ozgunes, Hilal and Sterner, Olov}}, issn = {{1307-6167}}, keywords = {{Geranium stepporum; Geraniaceae; galloylglucopyranose; hydrolysable; tannin; flavonoid; antioxidant effect}}, language = {{eng}}, number = {{1}}, pages = {{22--28}}, publisher = {{ACG Publications}}, series = {{Records of Natural Products}}, title = {{Polyphenolic Constituents and Antioxidant Potential of Geranium stepporum Davis}}, url = {{http://acgpubs.org/RNP/2011/Volume%205/Issue%201/3-RNP-1005-229.pdf}}, volume = {{5}}, year = {{2011}}, }