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Protein kinase C modulation of the ethanol effect on serotonin2 receptor transduction in astrocytes

Simonsson, Per LU ; Hansson, Elisabeth and Alling, Christer LU (1989) In Alcohol and Alcoholism 24(5). p.401-404
Abstract
Acute ethanol exposure stimulated serotonin2 receptor signalling in cultured astrocytes. Pretreatment with the protein kinase C inhibitor H7 significantly increased the ethanol-induced potentiation of [3H]-inositol phosphates accumulation. The increase could be explained by an augmented activation of phospholipase C. The results indicate a role of PKC for the modulation of ethanol effects on cellular signalling.
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Alcohol and Alcoholism
volume
24
issue
5
pages
401 - 404
publisher
Oxford University Press
external identifiers
  • pmid:2554934
  • scopus:0024829805
ISSN
1464-3502
language
English
LU publication?
yes
id
ef190104-f624-493e-a3a3-3ac25cf41b4c (old id 1104759)
alternative location
http://alcalc.oxfordjournals.org/cgi/reprint/24/5/401
date added to LUP
2016-04-01 12:29:31
date last changed
2021-01-03 07:35:28
@article{ef190104-f624-493e-a3a3-3ac25cf41b4c,
  abstract     = {{Acute ethanol exposure stimulated serotonin2 receptor signalling in cultured astrocytes. Pretreatment with the protein kinase C inhibitor H7 significantly increased the ethanol-induced potentiation of [3H]-inositol phosphates accumulation. The increase could be explained by an augmented activation of phospholipase C. The results indicate a role of PKC for the modulation of ethanol effects on cellular signalling.}},
  author       = {{Simonsson, Per and Hansson, Elisabeth and Alling, Christer}},
  issn         = {{1464-3502}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{401--404}},
  publisher    = {{Oxford University Press}},
  series       = {{Alcohol and Alcoholism}},
  title        = {{Protein kinase C modulation of the ethanol effect on serotonin2 receptor transduction in astrocytes}},
  url          = {{http://alcalc.oxfordjournals.org/cgi/reprint/24/5/401}},
  volume       = {{24}},
  year         = {{1989}},
}