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Diagnostic work up : Laboratory and biomarkers

Cedergren Weber, Gustav and Odin, Per LU orcid (2022) In International Review of Neurobiology 162. p.53-96
Abstract

This chapter will focus on the diagnostic work around sexual dysfunction in Parkinson's disease, especially laboratory tests and biomarkers. A number of methods to analyze if sexual dysfunction is caused by neural pathology, vascular dysfunction or other mechanisms are now available. Other methods can be used to differentiate between psychogenic/functional reasons behind sexual dysfunction and organic ones. The role of biomarkers for diagnosis, but also for understanding the reason behind and for counteracting sexual dysfunction is becoming more evident. There is also a rich and increasing number of scales and other instruments available for detecting and quantifying sexual hypo- and hyperactivity. When investigating the reason behind... (More)

This chapter will focus on the diagnostic work around sexual dysfunction in Parkinson's disease, especially laboratory tests and biomarkers. A number of methods to analyze if sexual dysfunction is caused by neural pathology, vascular dysfunction or other mechanisms are now available. Other methods can be used to differentiate between psychogenic/functional reasons behind sexual dysfunction and organic ones. The role of biomarkers for diagnosis, but also for understanding the reason behind and for counteracting sexual dysfunction is becoming more evident. There is also a rich and increasing number of scales and other instruments available for detecting and quantifying sexual hypo- and hyperactivity. When investigating the reason behind sexual dysfunction in patients with Parkinson's disease comorbidities should also be considered. Finally, early and pronounced sexual dysfunction might in some cases be an indication that differential diagnosis, like Multisystem Atrophy, should be thought about. All these aspects of the diagnostic procedures around sexual dysfunction in Parkinson's disease will be covered in this chapter.

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Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Biomarkers, Comorbidity, Diagnosis, Erectile dysfunction, Hypersexuality, Neuropathy, Parkinson's disease, Questionaries, Sexual dysfunction, Vasculopathy
host publication
International Review of Neurobiology
series title
International Review of Neurobiology
volume
162
pages
44 pages
publisher
Academic Press
external identifiers
  • pmid:35397789
  • scopus:85123260386
ISSN
0074-7742
2162-5514
DOI
10.1016/bs.irn.2021.12.003
language
English
LU publication?
yes
id
efbf29ec-b15a-4f09-bb2d-49ac468464d2
date added to LUP
2022-03-21 15:10:12
date last changed
2024-04-10 01:43:57
@inbook{efbf29ec-b15a-4f09-bb2d-49ac468464d2,
  abstract     = {{<p>This chapter will focus on the diagnostic work around sexual dysfunction in Parkinson's disease, especially laboratory tests and biomarkers. A number of methods to analyze if sexual dysfunction is caused by neural pathology, vascular dysfunction or other mechanisms are now available. Other methods can be used to differentiate between psychogenic/functional reasons behind sexual dysfunction and organic ones. The role of biomarkers for diagnosis, but also for understanding the reason behind and for counteracting sexual dysfunction is becoming more evident. There is also a rich and increasing number of scales and other instruments available for detecting and quantifying sexual hypo- and hyperactivity. When investigating the reason behind sexual dysfunction in patients with Parkinson's disease comorbidities should also be considered. Finally, early and pronounced sexual dysfunction might in some cases be an indication that differential diagnosis, like Multisystem Atrophy, should be thought about. All these aspects of the diagnostic procedures around sexual dysfunction in Parkinson's disease will be covered in this chapter.</p>}},
  author       = {{Cedergren Weber, Gustav and Odin, Per}},
  booktitle    = {{International Review of Neurobiology}},
  issn         = {{0074-7742}},
  keywords     = {{Biomarkers; Comorbidity; Diagnosis; Erectile dysfunction; Hypersexuality; Neuropathy; Parkinson's disease; Questionaries; Sexual dysfunction; Vasculopathy}},
  language     = {{eng}},
  pages        = {{53--96}},
  publisher    = {{Academic Press}},
  series       = {{International Review of Neurobiology}},
  title        = {{Diagnostic work up : Laboratory and biomarkers}},
  url          = {{http://dx.doi.org/10.1016/bs.irn.2021.12.003}},
  doi          = {{10.1016/bs.irn.2021.12.003}},
  volume       = {{162}},
  year         = {{2022}},
}