Long-term exposure to transportation noise and risk for atrial fibrillation : A Danish nationwide cohort study
(2022) In Environmental Research 207. p.1-7- Abstract
BACKGROUND: Epidemiological studies have linked transportation noise and cardiovascular diseases, however, atrial fibrillation (AF) has received limited attention. We aimed to investigate the association between transportation noise and AF risk.
METHODS: Over the period 1990-2017 we estimated road and railway noise (Lden) at the most and least exposed façades for all residential addresses across Denmark. We estimated time-weighted mean noise exposure for 3.6 million individuals age ≥35 years. Of these, 269,756 incident cases of AF were identified with a mean follow-up of 13.0 years. Analyses were conducted using Cox proportional hazards models with adjustment for individual and area-level sociodemographic covariates and long-term... (More)
BACKGROUND: Epidemiological studies have linked transportation noise and cardiovascular diseases, however, atrial fibrillation (AF) has received limited attention. We aimed to investigate the association between transportation noise and AF risk.
METHODS: Over the period 1990-2017 we estimated road and railway noise (Lden) at the most and least exposed façades for all residential addresses across Denmark. We estimated time-weighted mean noise exposure for 3.6 million individuals age ≥35 years. Of these, 269,756 incident cases of AF were identified with a mean follow-up of 13.0 years. Analyses were conducted using Cox proportional hazards models with adjustment for individual and area-level sociodemographic covariates and long-term residential air pollution.
RESULTS: A 10 dB higher 10-year mean road traffic noise at the most and least exposed façades were associated with incidence rate ratios (IRR) and 95% confidence intervals (CI) for AF of 1.006 (1.001-1.011) and 1.013 (1.007-1.019), respectively. After further adjustment for PM2.5, the IRRs (CIs) were 1.000 (0.995-1.005) and 1.007 (1.000-1.013), respectively. For railway noise, the IRRs per 10 dB increase in 10-year mean exposure were 1.017 (1.007-1.026) and 1.035 (1.021-1.050) for the most and least exposed façades, respectively, and were slightly attenuated when adjusted for PM2.5. Aircraft noise between 55 and 60 dB and ≥60 dB were associated with IRRs of 1.055 (0.996-1.116) and 1.036 (0.931-1.154), respectively, when compared to <45 dB.
CONCLUSION: Transportation noise seems to be associated with a small increase in AF risk, especially for exposure at the least exposed façade.
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- author
- Thacher, Jesse D LU ; Poulsen, Aslak H ; Hvidtfeldt, Ulla A ; Raaschou-Nielsen, Ole ; Ketzel, Matthias LU ; Jensen, Steen S ; Brandt, Jørgen ; Valencia, Victor H ; Münzel, Thomas and Sørensen, Mette
- publishing date
- 2022-05-01
- type
- Contribution to journal
- publication status
- published
- keywords
- Adult, Atrial Fibrillation/epidemiology, Cohort Studies, Denmark/epidemiology, Environmental Exposure/analysis, Humans, Noise, Transportation/adverse effects
- in
- Environmental Research
- volume
- 207
- article number
- 112167
- pages
- 1 - 7
- publisher
- Elsevier
- external identifiers
-
- scopus:85116553399
- pmid:34619123
- ISSN
- 1096-0953
- DOI
- 10.1016/j.envres.2021.112167
- language
- English
- LU publication?
- no
- additional info
- Copyright © 2021 Elsevier Inc. All rights reserved.
- id
- f13e5242-3964-49ae-84a5-e09d66eed801
- date added to LUP
- 2023-05-08 10:48:50
- date last changed
- 2024-04-19 21:35:34
@article{f13e5242-3964-49ae-84a5-e09d66eed801,
abstract = {{<p>BACKGROUND: Epidemiological studies have linked transportation noise and cardiovascular diseases, however, atrial fibrillation (AF) has received limited attention. We aimed to investigate the association between transportation noise and AF risk.</p><p>METHODS: Over the period 1990-2017 we estimated road and railway noise (Lden) at the most and least exposed façades for all residential addresses across Denmark. We estimated time-weighted mean noise exposure for 3.6 million individuals age ≥35 years. Of these, 269,756 incident cases of AF were identified with a mean follow-up of 13.0 years. Analyses were conducted using Cox proportional hazards models with adjustment for individual and area-level sociodemographic covariates and long-term residential air pollution.</p><p>RESULTS: A 10 dB higher 10-year mean road traffic noise at the most and least exposed façades were associated with incidence rate ratios (IRR) and 95% confidence intervals (CI) for AF of 1.006 (1.001-1.011) and 1.013 (1.007-1.019), respectively. After further adjustment for PM2.5, the IRRs (CIs) were 1.000 (0.995-1.005) and 1.007 (1.000-1.013), respectively. For railway noise, the IRRs per 10 dB increase in 10-year mean exposure were 1.017 (1.007-1.026) and 1.035 (1.021-1.050) for the most and least exposed façades, respectively, and were slightly attenuated when adjusted for PM2.5. Aircraft noise between 55 and 60 dB and ≥60 dB were associated with IRRs of 1.055 (0.996-1.116) and 1.036 (0.931-1.154), respectively, when compared to <45 dB.</p><p>CONCLUSION: Transportation noise seems to be associated with a small increase in AF risk, especially for exposure at the least exposed façade.</p>}},
author = {{Thacher, Jesse D and Poulsen, Aslak H and Hvidtfeldt, Ulla A and Raaschou-Nielsen, Ole and Ketzel, Matthias and Jensen, Steen S and Brandt, Jørgen and Valencia, Victor H and Münzel, Thomas and Sørensen, Mette}},
issn = {{1096-0953}},
keywords = {{Adult; Atrial Fibrillation/epidemiology; Cohort Studies; Denmark/epidemiology; Environmental Exposure/analysis; Humans; Noise, Transportation/adverse effects}},
language = {{eng}},
month = {{05}},
pages = {{1--7}},
publisher = {{Elsevier}},
series = {{Environmental Research}},
title = {{Long-term exposure to transportation noise and risk for atrial fibrillation : A Danish nationwide cohort study}},
url = {{http://dx.doi.org/10.1016/j.envres.2021.112167}},
doi = {{10.1016/j.envres.2021.112167}},
volume = {{207}},
year = {{2022}},
}