Intraductal papillary mucinous neoplasms of the pancreas: diagnosis and management.
(2010) In European Journal of Gastroenterology and Hepathology 22(9). p.1029-1038- Abstract
- Intraductal papillary mucinous neoplasms (IPMNs), characterized by intraductal papillary growth and thick mucin secretion, have increasingly been recognized. Despite modern preoperative evaluation, major difficulties still remain in distinguishing malignant invasive types from benign IPMNs. Following a PubMed database search, all relevant abstracts and articles on IPMN published in English and Chinese were reviewed. Main-duct and the mixed type IPMNs carry a higher risk of malignancy as compared with branch-duct type IPMNs. Treatment of branch-duct type IPMNs remains controversial. Once operation is indicated, intraoperative frozen section of margins plays an important role in the decision concerning the extent and type of surgery.... (More)
- Intraductal papillary mucinous neoplasms (IPMNs), characterized by intraductal papillary growth and thick mucin secretion, have increasingly been recognized. Despite modern preoperative evaluation, major difficulties still remain in distinguishing malignant invasive types from benign IPMNs. Following a PubMed database search, all relevant abstracts and articles on IPMN published in English and Chinese were reviewed. Main-duct and the mixed type IPMNs carry a higher risk of malignancy as compared with branch-duct type IPMNs. Treatment of branch-duct type IPMNs remains controversial. Once operation is indicated, intraoperative frozen section of margins plays an important role in the decision concerning the extent and type of surgery. Pancreatectomy, partly preserving both endocrine and exocrine pancreatic function, is advocated for most patients with IPMN, though total pancreatectomy may be necessary in some. Both for patients subjected to surgery and those only observed, IPMN patients need regular close follow-up to identify recurrence or progressive disease. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1626383
- author
- Liu, Dongbin LU ; Fei, Li ; Werner Josefin, Björk LU and Andersson, Roland LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Journal of Gastroenterology and Hepathology
- volume
- 22
- issue
- 9
- pages
- 1029 - 1038
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000280604500001
- pmid:20520560
- scopus:77955469347
- ISSN
- 1473-5687
- DOI
- 10.1097/MEG.0b013e32833b00f9
- language
- English
- LU publication?
- yes
- id
- f1987e13-9135-46bb-9ef4-cc319e871be5 (old id 1626383)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20520560?dopt=Abstract
- date added to LUP
- 2016-04-04 07:44:02
- date last changed
- 2022-01-29 02:32:50
@article{f1987e13-9135-46bb-9ef4-cc319e871be5, abstract = {{Intraductal papillary mucinous neoplasms (IPMNs), characterized by intraductal papillary growth and thick mucin secretion, have increasingly been recognized. Despite modern preoperative evaluation, major difficulties still remain in distinguishing malignant invasive types from benign IPMNs. Following a PubMed database search, all relevant abstracts and articles on IPMN published in English and Chinese were reviewed. Main-duct and the mixed type IPMNs carry a higher risk of malignancy as compared with branch-duct type IPMNs. Treatment of branch-duct type IPMNs remains controversial. Once operation is indicated, intraoperative frozen section of margins plays an important role in the decision concerning the extent and type of surgery. Pancreatectomy, partly preserving both endocrine and exocrine pancreatic function, is advocated for most patients with IPMN, though total pancreatectomy may be necessary in some. Both for patients subjected to surgery and those only observed, IPMN patients need regular close follow-up to identify recurrence or progressive disease.}}, author = {{Liu, Dongbin and Fei, Li and Werner Josefin, Björk and Andersson, Roland}}, issn = {{1473-5687}}, language = {{eng}}, number = {{9}}, pages = {{1029--1038}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{European Journal of Gastroenterology and Hepathology}}, title = {{Intraductal papillary mucinous neoplasms of the pancreas: diagnosis and management.}}, url = {{http://dx.doi.org/10.1097/MEG.0b013e32833b00f9}}, doi = {{10.1097/MEG.0b013e32833b00f9}}, volume = {{22}}, year = {{2010}}, }