Clinical impact of medication reviews for community-dwelling patients in primary healthcare
(2023) In BMC Primary Care 24(1).- Abstract
Background: A high number of drug-related problems has previously been shown among community-dwelling patients in primary healthcare in Skåne County, Sweden. Medication reviews are one way to solve these problems, but their impact is largely dependent on the process. We aimed to evaluate medication reviews for community-dwelling patients regarding the clinical relevance of the pharmacists’ recommendations, and their implementation by general practitioners. We also wanted to investigate if the general practitioners’ tendency to act on drug-related problems was correlated to different factors of the process. Methods: This was a cohort study, where patients in primary healthcare considered in need of a medication review were selected.... (More)
Background: A high number of drug-related problems has previously been shown among community-dwelling patients in primary healthcare in Skåne County, Sweden. Medication reviews are one way to solve these problems, but their impact is largely dependent on the process. We aimed to evaluate medication reviews for community-dwelling patients regarding the clinical relevance of the pharmacists’ recommendations, and their implementation by general practitioners. We also wanted to investigate if the general practitioners’ tendency to act on drug-related problems was correlated to different factors of the process. Methods: This was a cohort study, where patients in primary healthcare considered in need of a medication review were selected. Pharmacists identified drug-related problems and gave written recommendations on how to solve the problems to the general practitioner, via the medical record, and in addition in some cases via verbal communication. The clinical relevance of the recommendations was graded according to the Hatoum scale, ranging from one (adverse significance) to six (extremely significant). Descriptive statistics were used regarding the clinical relevance and the general practitioners´ tendency to act on drug-related problems. Multiple logistic regression analysis was used to examine the association between the tendency to act and different factors of the process. Results: A total of 96.1% of the 384 assessed recommendations from the pharmacists were graded as significant or more for the patient (Hatoum grade 3 or higher). The general practitioners acted on 63.8% of the drug-related problems. Fewer recommendations per patient, as well as verbal communication in addition to written contact, significantly increased the general practitioners’ tendency to act on a drug-related problem. No significant association was seen between the tendency to act and the clinical relevance of the recommendation. Conclusions: The high proportion of clinically relevant recommendations from the pharmacists in this study strengthens medication reviews as an important tool for reducing drug-related problems. Verbal communication between the pharmacist and the general practitioner is important for measures to be taken. Multiple recommendations for the same patient reduced their likelihood to of being addressed by the general practitioner.
(Less)
- author
- Dobszai, Annika LU ; Lenander, Cecilia LU ; Borgström Bolmsjö, Beata LU ; Wickman, Katarina LU and Modig, Sara LU
- organization
- publishing date
- 2023-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Clinical relevance, Drug-related problem, Independent living, Medication review, Pharmacist, clinical, Polypharmacy, Primary healthcare
- in
- BMC Primary Care
- volume
- 24
- issue
- 1
- article number
- 259
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:38042778
- scopus:85178335227
- ISSN
- 2731-4553
- DOI
- 10.1186/s12875-023-02216-0
- language
- English
- LU publication?
- yes
- additional info
- Funding Information: Open access funding provided by Lund University. The study was funded by The Kamprad Family Foundation for Entrepreneurship, Research and Charity, Lions Research Foundation, Skåne County and the Primary Care Research and Development in the County of Skåne. Funding Information: Thanks to the pharmacists performing the MRs, and the County Council in Region Skåne for providing financial and administrative support to this study. We wish to thank Anton Grundberg for his expertise in statistical analysis, and Patrick Reilly for valuable advice in reviewing the English language. We are also grateful to Krzysztof Grodon for the evaluation of clinical relevance, and to Sandra Jester-Broms for contributions to the analysis and interpretation of data. Publisher Copyright: © 2023, The Author(s).
- id
- f2de7b7c-3eb2-4324-87c6-817deb3d47e6
- date added to LUP
- 2023-12-21 12:41:39
- date last changed
- 2024-04-19 22:10:50
@article{f2de7b7c-3eb2-4324-87c6-817deb3d47e6,
abstract = {{<p>Background: A high number of drug-related problems has previously been shown among community-dwelling patients in primary healthcare in Skåne County, Sweden. Medication reviews are one way to solve these problems, but their impact is largely dependent on the process. We aimed to evaluate medication reviews for community-dwelling patients regarding the clinical relevance of the pharmacists’ recommendations, and their implementation by general practitioners. We also wanted to investigate if the general practitioners’ tendency to act on drug-related problems was correlated to different factors of the process. Methods: This was a cohort study, where patients in primary healthcare considered in need of a medication review were selected. Pharmacists identified drug-related problems and gave written recommendations on how to solve the problems to the general practitioner, via the medical record, and in addition in some cases via verbal communication. The clinical relevance of the recommendations was graded according to the Hatoum scale, ranging from one (adverse significance) to six (extremely significant). Descriptive statistics were used regarding the clinical relevance and the general practitioners´ tendency to act on drug-related problems. Multiple logistic regression analysis was used to examine the association between the tendency to act and different factors of the process. Results: A total of 96.1% of the 384 assessed recommendations from the pharmacists were graded as significant or more for the patient (Hatoum grade 3 or higher). The general practitioners acted on 63.8% of the drug-related problems. Fewer recommendations per patient, as well as verbal communication in addition to written contact, significantly increased the general practitioners’ tendency to act on a drug-related problem. No significant association was seen between the tendency to act and the clinical relevance of the recommendation. Conclusions: The high proportion of clinically relevant recommendations from the pharmacists in this study strengthens medication reviews as an important tool for reducing drug-related problems. Verbal communication between the pharmacist and the general practitioner is important for measures to be taken. Multiple recommendations for the same patient reduced their likelihood to of being addressed by the general practitioner.</p>}},
author = {{Dobszai, Annika and Lenander, Cecilia and Borgström Bolmsjö, Beata and Wickman, Katarina and Modig, Sara}},
issn = {{2731-4553}},
keywords = {{Clinical relevance; Drug-related problem; Independent living; Medication review; Pharmacist, clinical; Polypharmacy; Primary healthcare}},
language = {{eng}},
number = {{1}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Primary Care}},
title = {{Clinical impact of medication reviews for community-dwelling patients in primary healthcare}},
url = {{http://dx.doi.org/10.1186/s12875-023-02216-0}},
doi = {{10.1186/s12875-023-02216-0}},
volume = {{24}},
year = {{2023}},
}