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Differentsirovka neironov golubovatogo mesta posle ikh allotransplantatsii v predvaritel'no denervirovannyi gippokamp belykh krys.

Svanidze, I. K. ; Tsaishvili, T. S. ; Kokaia, Z. G. LU orcid ; Godziashvili, S. B. and Kokaia, M. G. LU (1997) In Morfologiia 111(2). p.35-39
Abstract

The suspension of embryonic locus coeruleus (LC) was transplanted into outbred albino rat hippocampus after its preliminary 6-hydroxy-dopamine-induced denervation. Immunohistochemical and morphometric analysis revealed that 3 months after the transplantation, embryonic noradrenergic LC cells which have completed their histogenesis in recipient hippocampus, appear as differentiated multipolar and fusiform cells, typical to LC. Intrahippocampal allotransplants of rat embryonic LC were also demonstrated to normalize the level of orientation activity in an open area, that was significantly reduced after administration of 6-hydroxy-dopamine to the animals.

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author
; ; ; and
organization
alternative title
The differentiation of locus coeruleus neurons after their allotransplantation into the preliminarily denervated hippocampus of white rats
publishing date
type
Contribution to journal
publication status
published
in
Morfologiia
volume
111
issue
2
pages
5 pages
publisher
Morfologiya
external identifiers
  • pmid:9244545
  • scopus:0030624057
ISSN
1026-3543
language
Russian
LU publication?
yes
id
f2e2f7ed-b29d-41f9-846f-e28d368367c3
date added to LUP
2019-09-03 17:06:29
date last changed
2024-01-01 18:46:18
@article{f2e2f7ed-b29d-41f9-846f-e28d368367c3,
  abstract     = {{<p>The suspension of embryonic locus coeruleus (LC) was transplanted into outbred albino rat hippocampus after its preliminary 6-hydroxy-dopamine-induced denervation. Immunohistochemical and morphometric analysis revealed that 3 months after the transplantation, embryonic noradrenergic LC cells which have completed their histogenesis in recipient hippocampus, appear as differentiated multipolar and fusiform cells, typical to LC. Intrahippocampal allotransplants of rat embryonic LC were also demonstrated to normalize the level of orientation activity in an open area, that was significantly reduced after administration of 6-hydroxy-dopamine to the animals.</p>}},
  author       = {{Svanidze, I. K. and Tsaishvili, T. S. and Kokaia, Z. G. and Godziashvili, S. B. and Kokaia, M. G.}},
  issn         = {{1026-3543}},
  language     = {{rus}},
  month        = {{08}},
  number       = {{2}},
  pages        = {{35--39}},
  publisher    = {{Morfologiya}},
  series       = {{Morfologiia}},
  title        = {{Differentsirovka neironov golubovatogo mesta posle ikh allotransplantatsii v predvaritel'no denervirovannyi gippokamp belykh krys.}},
  volume       = {{111}},
  year         = {{1997}},
}