Anthropometric measures in relation to risk of heart failure hospitalization: a Swedish population-based cohort study.
(2014) In European Journal of Public Health 24(2). p.215-220- Abstract
- BACKGROUND: It is unclear which anthropometric measure is most useful for assessment of the cardiovascular risk. We investigated the association between different anthropometric measures and risk of heart failure (HF) hospitalization. METHODS: BMI, waist-hip ratio (WHR), waist circumference (WC), body fat percentage (BF%), weight and height were measured among 26 653 subjects (aged 45-73 years) without history of myocardial infarction (MI), stroke or HF from the Malmö Diet and Cancer cohort at baseline in 1991-96. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years. RESULTS: Seven hundred and twenty-seven subjects were hospitalized with HF as primary diagnosis, of whom 157 had an MI before or concurrent with... (More)
- BACKGROUND: It is unclear which anthropometric measure is most useful for assessment of the cardiovascular risk. We investigated the association between different anthropometric measures and risk of heart failure (HF) hospitalization. METHODS: BMI, waist-hip ratio (WHR), waist circumference (WC), body fat percentage (BF%), weight and height were measured among 26 653 subjects (aged 45-73 years) without history of myocardial infarction (MI), stroke or HF from the Malmö Diet and Cancer cohort at baseline in 1991-96. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years. RESULTS: Seven hundred and twenty-seven subjects were hospitalized with HF as primary diagnosis, of whom 157 had an MI before or concurrent with the HF. After adjustment for potential confounding factors, the hazard ratios of HF hospitalization (fourth vs. first sex-specific quartile) were 1.80 (95% CI: 1.45-2.24) for BMI, 1.87 (1.50-2.34) for WC, 1.77 (1.43-2.19) for WHR, 1.35 (1.09-1.68) for BF%, 1.93 (1.57-2.39) for weight and 1.18 (0.96-1.44) for height. Significant interactions between BMI and WC and WHR, respectively, were observed, and the joint exposure of high BMI and high WC or high WHR further increased the risk. The results were similar in secondary analyses, i.e. excluding incident HF with previous MI during the follow-up. CONCLUSION: Our results support the view that raised BMI, WC, WHR or BF% increases the risk of HF hospitalization. The joint exposure of high BMI and high WHR or high WC further increased the risk in an additive way. (Less)
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https://lup.lub.lu.se/record/3218481
- author
- Borné, Yan LU ; Hedblad, Bo LU ; Essén, Birgitta LU and Engström, Gunnar LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Journal of Public Health
- volume
- 24
- issue
- 2
- pages
- 215 - 220
- publisher
- Oxford University Press
- external identifiers
-
- pmid:23183497
- wos:000334101000012
- scopus:84897442703
- pmid:23183497
- ISSN
- 1101-1262
- DOI
- 10.1093/eurpub/cks161
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Cardio-vascular Epidemiology (013241610)
- id
- f338f146-3149-4239-bf07-c42f633cd91a (old id 3218481)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23183497?dopt=Abstract
- date added to LUP
- 2016-04-01 10:21:36
- date last changed
- 2022-04-04 17:17:49
@article{f338f146-3149-4239-bf07-c42f633cd91a, abstract = {{BACKGROUND: It is unclear which anthropometric measure is most useful for assessment of the cardiovascular risk. We investigated the association between different anthropometric measures and risk of heart failure (HF) hospitalization. METHODS: BMI, waist-hip ratio (WHR), waist circumference (WC), body fat percentage (BF%), weight and height were measured among 26 653 subjects (aged 45-73 years) without history of myocardial infarction (MI), stroke or HF from the Malmö Diet and Cancer cohort at baseline in 1991-96. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years. RESULTS: Seven hundred and twenty-seven subjects were hospitalized with HF as primary diagnosis, of whom 157 had an MI before or concurrent with the HF. After adjustment for potential confounding factors, the hazard ratios of HF hospitalization (fourth vs. first sex-specific quartile) were 1.80 (95% CI: 1.45-2.24) for BMI, 1.87 (1.50-2.34) for WC, 1.77 (1.43-2.19) for WHR, 1.35 (1.09-1.68) for BF%, 1.93 (1.57-2.39) for weight and 1.18 (0.96-1.44) for height. Significant interactions between BMI and WC and WHR, respectively, were observed, and the joint exposure of high BMI and high WC or high WHR further increased the risk. The results were similar in secondary analyses, i.e. excluding incident HF with previous MI during the follow-up. CONCLUSION: Our results support the view that raised BMI, WC, WHR or BF% increases the risk of HF hospitalization. The joint exposure of high BMI and high WHR or high WC further increased the risk in an additive way.}}, author = {{Borné, Yan and Hedblad, Bo and Essén, Birgitta and Engström, Gunnar}}, issn = {{1101-1262}}, language = {{eng}}, number = {{2}}, pages = {{215--220}}, publisher = {{Oxford University Press}}, series = {{European Journal of Public Health}}, title = {{Anthropometric measures in relation to risk of heart failure hospitalization: a Swedish population-based cohort study.}}, url = {{http://dx.doi.org/10.1093/eurpub/cks161}}, doi = {{10.1093/eurpub/cks161}}, volume = {{24}}, year = {{2014}}, }