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Prolonged survival time of Daphnia magna exposed to polylactic acid breakdown nanoplastics

Kelpsiene, Egle LU ; Rydberg, Melinda LU ; Ekvall, Mikael T. LU ; Lundqvist, Martin LU and Cedervall, Tommy LU (2023) In PLoS ONE 18(9).
Abstract
Polylactic acid nanoparticles (PLA NPs) according to food and drug administration are biodegradable and biocompatible polymers that have received a lot of attention due to their natural degradation mechanism. Although there is already available information concerning the effects of PLA microplastic to aquatic organisms, the knowledge about PLA NPs is still vague. In the present study, we analyzed the chemical composition of engineered PLA NPs, daily used PLA items and their breakdown products. We show that PLA breakdown products are oxidized and may contain aldehydes and/or ketones. The breakdown produces nanosized particles, nanoplastics, and possibly other small molecules as lactide or cyclic oligomers. Further, we show that all PLA... (More)
Polylactic acid nanoparticles (PLA NPs) according to food and drug administration are biodegradable and biocompatible polymers that have received a lot of attention due to their natural degradation mechanism. Although there is already available information concerning the effects of PLA microplastic to aquatic organisms, the knowledge about PLA NPs is still vague. In the present study, we analyzed the chemical composition of engineered PLA NPs, daily used PLA items and their breakdown products. We show that PLA breakdown products are oxidized and may contain aldehydes and/or ketones. The breakdown produces nanosized particles, nanoplastics, and possibly other small molecules as lactide or cyclic oligomers. Further, we show that all PLA breakdown nanoplastics extended the survival rate in Daphnia magna in an acute toxicity assay, however, only PLA plastic cup breakdown nanoplastics showed a significant difference compared to a control group. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
18
issue
9
pages
14 pages
publisher
Public Library of Science (PLoS)
external identifiers
  • pmid:37669271
  • scopus:85169759989
ISSN
1932-6203
DOI
10.1371/journal.pone.0290748
language
English
LU publication?
yes
id
f5009e46-b5d6-49d2-b8f5-748724e3f813
date added to LUP
2023-09-06 13:14:24
date last changed
2024-05-09 08:08:29
@article{f5009e46-b5d6-49d2-b8f5-748724e3f813,
  abstract     = {{Polylactic acid nanoparticles (PLA NPs) according to food and drug administration are biodegradable and biocompatible polymers that have received a lot of attention due to their natural degradation mechanism. Although there is already available information concerning the effects of PLA microplastic to aquatic organisms, the knowledge about PLA NPs is still vague. In the present study, we analyzed the chemical composition of engineered PLA NPs, daily used PLA items and their breakdown products. We show that PLA breakdown products are oxidized and may contain aldehydes and/or ketones. The breakdown produces nanosized particles, nanoplastics, and possibly other small molecules as lactide or cyclic oligomers. Further, we show that all PLA breakdown nanoplastics extended the survival rate in Daphnia magna in an acute toxicity assay, however, only PLA plastic cup breakdown nanoplastics showed a significant difference compared to a control group.}},
  author       = {{Kelpsiene, Egle and Rydberg, Melinda and Ekvall, Mikael T. and Lundqvist, Martin and Cedervall, Tommy}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  month        = {{09}},
  number       = {{9}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{Prolonged survival time of <i>Daphnia magna</i> exposed to polylactic acid breakdown nanoplastics}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0290748}},
  doi          = {{10.1371/journal.pone.0290748}},
  volume       = {{18}},
  year         = {{2023}},
}