Selection of collimator for rCBF studies and evaluation of triple-headed SPET using noise-resolution plots
(1997) In Nuclear Medicine Communications 18(7). p.655-661- Abstract
- We investigated the effect of collimator selection on image quality in regional cerebral blood flow (rCBF) studies of the brain performed with 99Tc(m)-HMPAO. A triple-headed SPET system (GE/CGR Neurocam) was used, together with three sets of parallel-hole collimators - general-purpose (GP), high-resolution (HR) and ultra-high-resolution (UHR). Two image quality parameters were used to describe the image quality, namely, noise and resolution. Noise was measured in experimental and Monte-Carlo simulated SPET studies of a cylinder phantom of uniform activity as the pixel root mean square error (RMS) and as the coefficient of variation (CV) of quantitative rCBF values. Resolution was measured as full-width at half-maximum in experimental SPET... (More)
- We investigated the effect of collimator selection on image quality in regional cerebral blood flow (rCBF) studies of the brain performed with 99Tc(m)-HMPAO. A triple-headed SPET system (GE/CGR Neurocam) was used, together with three sets of parallel-hole collimators - general-purpose (GP), high-resolution (HR) and ultra-high-resolution (UHR). Two image quality parameters were used to describe the image quality, namely, noise and resolution. Noise was measured in experimental and Monte-Carlo simulated SPET studies of a cylinder phantom of uniform activity as the pixel root mean square error (RMS) and as the coefficient of variation (CV) of quantitative rCBF values. Resolution was measured as full-width at half-maximum in experimental SPET studies of a line-source. Plots of noise versus resolution for the different collimators were obtained by varying the cut-off frequency of the Hanning filter applied in the reconstruction of transaxial slices. From these noise-resolution plots, we were able to determine which collimator gave the best resolution for a specific noise level. A lowest reasonable noise level may be established by comparison with the inter-observer CV of the quantification method. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1111891
- author
- Ärlig, A ; Jacobsson, L ; Larsson, A ; Ljungberg, Michael LU and Wikkelso, C
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nuclear Medicine Communications
- volume
- 18
- issue
- 7
- pages
- 655 - 661
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:9342104
- scopus:0030761579
- ISSN
- 1473-5628
- language
- English
- LU publication?
- yes
- id
- f6bb4898-6a41-49d8-9bf4-d572f81fd2d2 (old id 1111891)
- date added to LUP
- 2016-04-01 11:42:40
- date last changed
- 2022-01-26 17:06:28
@article{f6bb4898-6a41-49d8-9bf4-d572f81fd2d2, abstract = {{We investigated the effect of collimator selection on image quality in regional cerebral blood flow (rCBF) studies of the brain performed with 99Tc(m)-HMPAO. A triple-headed SPET system (GE/CGR Neurocam) was used, together with three sets of parallel-hole collimators - general-purpose (GP), high-resolution (HR) and ultra-high-resolution (UHR). Two image quality parameters were used to describe the image quality, namely, noise and resolution. Noise was measured in experimental and Monte-Carlo simulated SPET studies of a cylinder phantom of uniform activity as the pixel root mean square error (RMS) and as the coefficient of variation (CV) of quantitative rCBF values. Resolution was measured as full-width at half-maximum in experimental SPET studies of a line-source. Plots of noise versus resolution for the different collimators were obtained by varying the cut-off frequency of the Hanning filter applied in the reconstruction of transaxial slices. From these noise-resolution plots, we were able to determine which collimator gave the best resolution for a specific noise level. A lowest reasonable noise level may be established by comparison with the inter-observer CV of the quantification method.}}, author = {{Ärlig, A and Jacobsson, L and Larsson, A and Ljungberg, Michael and Wikkelso, C}}, issn = {{1473-5628}}, language = {{eng}}, number = {{7}}, pages = {{655--661}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{Nuclear Medicine Communications}}, title = {{Selection of collimator for rCBF studies and evaluation of triple-headed SPET using noise-resolution plots}}, volume = {{18}}, year = {{1997}}, }