Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform.
Dykes, Josefina LU ; Lenshof, Andreas LU
; Åstrand-Grundström, Ingbritt
LU
; Laurell, Thomas
LU
and Scheding, Stefan
LU
(2011)
In PLoS ONE
6(8).
- Abstract
- Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated a novel microchip-based acoustophoresis technique, utilizing ultrasonic standing wave forces for the removal of platelets from PBPC products. By applying an acoustic standing wave field onto a continuously flowing cell suspension in a micro channel, cells can be separated from the surrounding media depending on their physical properties.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2150804
- author
- Dykes, Josefina
LU
; Lenshof, Andreas
LU
; Åstrand-Grundström, Ingbritt
LU
; Laurell, Thomas
LU
and Scheding, Stefan
LU
- organization
-
- Division of Hematology and Clinical Immunology
- Division for Biomedical Engineering
- Stem Cell Center
- Bone marrow stem cells and cellular therapies (research group)
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
- MultiPark: Multidisciplinary research focused on Parkinson's disease
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 6
- issue
- 8
- article number
- e23074
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- wos:000293774300020
- pmid:21857996
- scopus:79961216177
- pmid:21857996
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0023074
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Hematology and Transfusion Medicine (013041100), Stem Cell Center (013022011), Biomedical Engineering (011200011), Hematopoietic Stem Cell Laboratory (013022012), Hematology/Transplantation (013022014)
- id
- f8a2f731-6830-4b16-bdbb-59bf64fc355e (old id 2150804)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21857996?dopt=Abstract
- date added to LUP
- 2016-04-04 09:23:49
- date last changed
- 2025-10-14 12:01:25
@article{f8a2f731-6830-4b16-bdbb-59bf64fc355e,
abstract = {{Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated a novel microchip-based acoustophoresis technique, utilizing ultrasonic standing wave forces for the removal of platelets from PBPC products. By applying an acoustic standing wave field onto a continuously flowing cell suspension in a micro channel, cells can be separated from the surrounding media depending on their physical properties.}},
author = {{Dykes, Josefina and Lenshof, Andreas and Åstrand-Grundström, Ingbritt and Laurell, Thomas and Scheding, Stefan}},
issn = {{1932-6203}},
language = {{eng}},
number = {{8}},
publisher = {{Public Library of Science (PLoS)}},
series = {{PLoS ONE}},
title = {{Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform.}},
url = {{https://lup.lub.lu.se/search/files/5313226/2256507.pdf}},
doi = {{10.1371/journal.pone.0023074}},
volume = {{6}},
year = {{2011}},
}