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Sleeping habits and aortic stiffness in middle-aged men and women from the general population: insights from the SCAPIS study

Johansson, Madeleine LU orcid ; Östgren, Carl Johan LU ; Nilsson, Peter M. LU ; Engvall, Jan and Engström, Gunnar LU (2024) In Blood Pressure 33(1).
Abstract
Background
The relationship between sleeping habits and aortic stiffness remains inconclusive and is not fully explored in the European general population.

Methods
We examined cross-sectionally 8659 participants from the Swedish population-based cohort Swedish CArdioPulmonary bioImage Study (SCAPIS), mean age 57.5 years, 52.1% women. A self-administered questionnaire on sleeping habits (duration, quality, insomnia, and daytime sleepiness) was administered. Aortic stiffness was examined by the gold-standard method, carotid-femoral pulse wave velocity (c-f PWV) using Sphygmocor® XCEL, continuously and stratified by cut-off of >10 m/s. Multivariable linear and logistic regression were performed stratified by... (More)
Background
The relationship between sleeping habits and aortic stiffness remains inconclusive and is not fully explored in the European general population.

Methods
We examined cross-sectionally 8659 participants from the Swedish population-based cohort Swedish CArdioPulmonary bioImage Study (SCAPIS), mean age 57.5 years, 52.1% women. A self-administered questionnaire on sleeping habits (duration, quality, insomnia, and daytime sleepiness) was administered. Aortic stiffness was examined by the gold-standard method, carotid-femoral pulse wave velocity (c-f PWV) using Sphygmocor® XCEL, continuously and stratified by cut-off of >10 m/s. Multivariable linear and logistic regression were performed stratified by sex.

Results
Out of 8659 subjects (mean c-f PWV of 9.4 ± 1.9 m/s), 32.3% had c-f PWV >10 m/s, defined as aortic stiffness. Compared with subjects with c-f PWV ≤10 m/s, individuals with aortic stiffness reported more insomnia (p = 0.01) but less daytime sleepiness (p = 0.008). Men and women with poor sleep quality had 0.2 m/s lower mean c-f PWV compared with subjects with good sleep quality (p = 0.004). No difference in mean PWV was found in men and women with shorter/longer sleep duration (p > 0.05). In the multivariable regression models, no significant association was found between poor sleep quality, shorter (≤6 h) or longer (≥9 h) sleep duration and aortic stiffness in the total population, neither among men nor women (all p > 0.05), independently of cardiovascular risk factors.

Conclusions
Short and long sleep duration and poor sleep quality are not associated with aortic stiffness, measured with the gold-standard method c-f-PWV, in middle-aged men and women from the Swedish general population, independently of cardiovascular risk factors. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
aortic stiffness, sleep
in
Blood Pressure
volume
33
issue
1
article number
2424825
publisher
Informa Healthcare
external identifiers
  • scopus:85209157976
  • pmid:39513329
ISSN
0803-7051
DOI
10.1080/08037051.2024.2424825
project
Vascular Ageing and Arterial Stiffness in the Swedish Population
language
English
LU publication?
yes
id
fb5bb51f-8034-4fc3-a309-56ee874e5663
date added to LUP
2024-11-08 15:23:05
date last changed
2025-04-04 15:24:49
@article{fb5bb51f-8034-4fc3-a309-56ee874e5663,
  abstract     = {{Background<br/>The relationship between sleeping habits and aortic stiffness remains inconclusive and is not fully explored in the European general population.<br/><br/>Methods<br/>We examined cross-sectionally 8659 participants from the Swedish population-based cohort Swedish CArdioPulmonary bioImage Study (SCAPIS), mean age 57.5 years, 52.1% women. A self-administered questionnaire on sleeping habits (duration, quality, insomnia, and daytime sleepiness) was administered. Aortic stiffness was examined by the gold-standard method, carotid-femoral pulse wave velocity (c-f PWV) using Sphygmocor® XCEL, continuously and stratified by cut-off of &gt;10 m/s. Multivariable linear and logistic regression were performed stratified by sex.<br/><br/>Results<br/>Out of 8659 subjects (mean c-f PWV of 9.4 ± 1.9 m/s), 32.3% had c-f PWV &gt;10 m/s, defined as aortic stiffness. Compared with subjects with c-f PWV ≤10 m/s, individuals with aortic stiffness reported more insomnia (p = 0.01) but less daytime sleepiness (p = 0.008). Men and women with poor sleep quality had 0.2 m/s lower mean c-f PWV compared with subjects with good sleep quality (p = 0.004). No difference in mean PWV was found in men and women with shorter/longer sleep duration (p &gt; 0.05). In the multivariable regression models, no significant association was found between poor sleep quality, shorter (≤6 h) or longer (≥9 h) sleep duration and aortic stiffness in the total population, neither among men nor women (all p &gt; 0.05), independently of cardiovascular risk factors.<br/><br/>Conclusions<br/>Short and long sleep duration and poor sleep quality are not associated with aortic stiffness, measured with the gold-standard method c-f-PWV, in middle-aged men and women from the Swedish general population, independently of cardiovascular risk factors.}},
  author       = {{Johansson, Madeleine and Östgren, Carl Johan and Nilsson, Peter M. and Engvall, Jan and Engström, Gunnar}},
  issn         = {{0803-7051}},
  keywords     = {{aortic stiffness; sleep}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{1}},
  publisher    = {{Informa Healthcare}},
  series       = {{Blood Pressure}},
  title        = {{Sleeping habits and aortic stiffness in middle-aged men and women from the general population: insights from the SCAPIS study}},
  url          = {{http://dx.doi.org/10.1080/08037051.2024.2424825}},
  doi          = {{10.1080/08037051.2024.2424825}},
  volume       = {{33}},
  year         = {{2024}},
}