Surveillance of Vaccine Safety: Comparison of parental reports with routine surveillance and a clinical trial
(2009) In Vaccine 27(14). p.2042-2047- Abstract
- One way to maintain confidence in vaccination programmes is to improve monitoring of immunisation safety. We studied active parental reporting of adverse events after a booster dose of diphtheria-tetanus toxoid (DT). 7193 children received the vaccine. Questionnaires were submitted by 84.2% of the parents, who reported reactions for 9.2% of the children. Four percent of events were classified as moderate/severe by interviews. Relative risk of redness and swelling reported was 0.24 (95% CI. 0.13-0.42) compared to a clinical trial, while it was 71.0 (44-114) compared to passive surveillance. Active surveillance by parental reports is a useful complement to passive surveillance of childhood immunisations to generate hypotheses for evaluation... (More)
- One way to maintain confidence in vaccination programmes is to improve monitoring of immunisation safety. We studied active parental reporting of adverse events after a booster dose of diphtheria-tetanus toxoid (DT). 7193 children received the vaccine. Questionnaires were submitted by 84.2% of the parents, who reported reactions for 9.2% of the children. Four percent of events were classified as moderate/severe by interviews. Relative risk of redness and swelling reported was 0.24 (95% CI. 0.13-0.42) compared to a clinical trial, while it was 71.0 (44-114) compared to passive surveillance. Active surveillance by parental reports is a useful complement to passive surveillance of childhood immunisations to generate hypotheses for evaluation in controlled studies. (C) 2009 Elsevier Ltd. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1401296
- author
- Netterlid, Eva LU ; Edwinson Månsson, Marie LU and Håkansson, Anders LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Local reactions, Vaccine safety, Parental reports
- in
- Vaccine
- volume
- 27
- issue
- 14
- pages
- 2042 - 2047
- publisher
- Elsevier
- external identifiers
-
- wos:000264680700009
- scopus:61549086525
- ISSN
- 1873-2518
- DOI
- 10.1016/j.vaccine.2009.01.131
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Nursing (Closed 2012) (013065000), Family Medicine (013241010)
- id
- fc8de849-b9a8-491d-8dce-4bf518305f7a (old id 1401296)
- date added to LUP
- 2016-04-01 12:21:01
- date last changed
- 2022-01-27 02:29:26
@article{fc8de849-b9a8-491d-8dce-4bf518305f7a,
abstract = {{One way to maintain confidence in vaccination programmes is to improve monitoring of immunisation safety. We studied active parental reporting of adverse events after a booster dose of diphtheria-tetanus toxoid (DT). 7193 children received the vaccine. Questionnaires were submitted by 84.2% of the parents, who reported reactions for 9.2% of the children. Four percent of events were classified as moderate/severe by interviews. Relative risk of redness and swelling reported was 0.24 (95% CI. 0.13-0.42) compared to a clinical trial, while it was 71.0 (44-114) compared to passive surveillance. Active surveillance by parental reports is a useful complement to passive surveillance of childhood immunisations to generate hypotheses for evaluation in controlled studies. (C) 2009 Elsevier Ltd. All rights reserved.}},
author = {{Netterlid, Eva and Edwinson Månsson, Marie and Håkansson, Anders}},
issn = {{1873-2518}},
keywords = {{Local reactions; Vaccine safety; Parental reports}},
language = {{eng}},
number = {{14}},
pages = {{2042--2047}},
publisher = {{Elsevier}},
series = {{Vaccine}},
title = {{Surveillance of Vaccine Safety: Comparison of parental reports with routine surveillance and a clinical trial}},
url = {{http://dx.doi.org/10.1016/j.vaccine.2009.01.131}},
doi = {{10.1016/j.vaccine.2009.01.131}},
volume = {{27}},
year = {{2009}},
}