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Flow field-flow fractionation: Critical overview.

Wahlund, Karl-Gustav LU (2013) In Journal of Chromatography A 1287. p.97-112
Abstract
This overview regards some critical issues in performing flow field-flow fractionation (flow FFF, FlFFF, AF4, HF-FlFFF, HF5). It includes the channel thickness, void time, channel-flow parabolic profile, channel-flow velocity gradient, uniformity of the cross-flow, sample injection time, relaxation/focusing time, width of sample starting zone, retention level, theoretical and experimental zone broadening, hydrodynamic threshold immobilisation/re-mobilisation, sample loss and adsorption, membrane fouling, sample mass overloading, problems with symmetrical channels, non-spherical sample particles, and method development. Good method development practice (GMDP) and good fractogram practice (GFP) is suggested.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Chromatography A
volume
1287
pages
97 - 112
publisher
Elsevier
external identifiers
  • wos:000317554400012
  • pmid:23510956
  • scopus:84875682235
  • pmid:23510956
ISSN
0021-9673
DOI
10.1016/j.chroma.2013.02.028
language
English
LU publication?
yes
id
ff37d075-768a-4f13-a35d-553fd712249d (old id 3627931)
date added to LUP
2016-04-01 10:50:07
date last changed
2025-04-04 14:57:10
@article{ff37d075-768a-4f13-a35d-553fd712249d,
  abstract     = {{This overview regards some critical issues in performing flow field-flow fractionation (flow FFF, FlFFF, AF4, HF-FlFFF, HF5). It includes the channel thickness, void time, channel-flow parabolic profile, channel-flow velocity gradient, uniformity of the cross-flow, sample injection time, relaxation/focusing time, width of sample starting zone, retention level, theoretical and experimental zone broadening, hydrodynamic threshold immobilisation/re-mobilisation, sample loss and adsorption, membrane fouling, sample mass overloading, problems with symmetrical channels, non-spherical sample particles, and method development. Good method development practice (GMDP) and good fractogram practice (GFP) is suggested.}},
  author       = {{Wahlund, Karl-Gustav}},
  issn         = {{0021-9673}},
  language     = {{eng}},
  pages        = {{97--112}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Chromatography A}},
  title        = {{Flow field-flow fractionation: Critical overview.}},
  url          = {{http://dx.doi.org/10.1016/j.chroma.2013.02.028}},
  doi          = {{10.1016/j.chroma.2013.02.028}},
  volume       = {{1287}},
  year         = {{2013}},
}