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- 2019
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Mark
Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-b aggregates
(
- Contribution to journal › Article
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Mark
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
(
- Contribution to journal › Article
- 2018
-
Mark
SAR by kinetics for drug discovery in protein misfolding diseases
2018) In Proceedings of the National Academy of Sciences of the United States of America 115(41). p.10245-10250(
- Contribution to journal › Article
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Mark
Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide
(
- Contribution to journal › Article
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Mark
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
(
- Contribution to journal › Article
- 2017
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Mark
Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants
(
- Contribution to journal › Article
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Mark
Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(30). p.8005-8010(
- Contribution to journal › Article
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Mark
Selective targeting of primary and secondary nucleation pathways in Ab42 aggregation using a rational antibody scanning method
(
- Contribution to journal › Article
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Mark
Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(25). p.6444-6449(
- Contribution to journal › Article
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Mark
Scaling behaviour and rate-determining steps in filamentous self-assembly
(
- Contribution to journal › Article