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- 2021
- A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
- 2020
- Structural characterization of covalently stabilized human cystatin c oligomers
- Kinetic diversity of amyloid oligomers
- Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors
- Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter
-
Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation
Flagmeier, Patrick ; De, Suman ; Michaels, Thomas C.T. ; Yang, Xiaoting LU ; Dear, Alexander J. ; Emanuelsson, Cecilia LU
; Vendruscolo, Michele
; Linse, Sara
LU
; Klenerman, David
and Knowles, Tuomas P.J.
, et al.
(2020)
In Nature Structural and Molecular Biology
27(10).
p.886-891
Mark
- Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
- Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies
- 2019
- Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils
- Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42