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Efficiency of liposomal and micellar emulsifiers during homogenization

Sunneskär, Ellen LU (2012) KEMN10 20112
Department of Chemistry
Abstract
The coalescence of emulsion droplets during the homogenization process is governed by the emulsifier adsorption rate. This is in turn affected by the size and shape of the adsorbing molecule which can be dependant of the aggregation states.
The aim of this thesis was to develop a model system suitable for measuring the efficiency of emulsifier during homogenization and to evaluate the hypothesis that the efficiency is dependant of the emulsifier aggregation state. The idea was to compare the degree of coalescence during emulsification when the emulsifier is adsorbing from a micellar respectively liposomal dispersion. The intension was to do this by using the method of fluorescence. The liposomes used were soybean phosphatidylcholine (PC)... (More)
The coalescence of emulsion droplets during the homogenization process is governed by the emulsifier adsorption rate. This is in turn affected by the size and shape of the adsorbing molecule which can be dependant of the aggregation states.
The aim of this thesis was to develop a model system suitable for measuring the efficiency of emulsifier during homogenization and to evaluate the hypothesis that the efficiency is dependant of the emulsifier aggregation state. The idea was to compare the degree of coalescence during emulsification when the emulsifier is adsorbing from a micellar respectively liposomal dispersion. The intension was to do this by using the method of fluorescence. The liposomes used were soybean phosphatidylcholine (PC) and mixed micelles of sodium cholate (NaC) and PC.
The efficiency of liposomal and micellar emulsifiers during homogenization could not be evaluated. The liposomes had no emulsifying properties possibly due to insufficient mixing and in the current case poor solubility of lecithin in the aqueous phase. The mixed micelles could not be formed. The methods used in this work are not to be recommended since the emulsifier must be soluble in the aqueous phase and the desired aggregation state easily prepared. (Less)
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author
Sunneskär, Ellen LU
supervisor
organization
course
KEMN10 20112
year
type
H2 - Master's Degree (Two Years)
subject
keywords
Nanokemi
language
English
id
3563089
date added to LUP
2013-03-12 11:17:07
date last changed
2013-03-12 11:17:07
@misc{3563089,
  abstract     = {The coalescence of emulsion droplets during the homogenization process is governed by the emulsifier adsorption rate. This is in turn affected by the size and shape of the adsorbing molecule which can be dependant of the aggregation states.
The aim of this thesis was to develop a model system suitable for measuring the efficiency of emulsifier during homogenization and to evaluate the hypothesis that the efficiency is dependant of the emulsifier aggregation state. The idea was to compare the degree of coalescence during emulsification when the emulsifier is adsorbing from a micellar respectively liposomal dispersion. The intension was to do this by using the method of fluorescence. The liposomes used were soybean phosphatidylcholine (PC) and mixed micelles of sodium cholate (NaC) and PC.
The efficiency of liposomal and micellar emulsifiers during homogenization could not be evaluated. The liposomes had no emulsifying properties possibly due to insufficient mixing and in the current case poor solubility of lecithin in the aqueous phase. The mixed micelles could not be formed. The methods used in this work are not to be recommended since the emulsifier must be soluble in the aqueous phase and the desired aggregation state easily prepared.},
  author       = {Sunneskär, Ellen},
  keyword      = {Nanokemi},
  language     = {eng},
  note         = {Student Paper},
  title        = {Efficiency of liposomal and micellar emulsifiers during homogenization},
  year         = {2012},
}