Effect of Oat Bio-actives on Cardiometabolic Related Variables in Humans
(2021) KNLM01 20211Food Technology and Nutrition (M.Sc.)
- Abstract
- Consumers are becoming interested in oats as a healthy food. Several studies have investigated the impact of oats components on human metabolism. The purpose of this project is to study the influence of oat polar lipids on human cardiometabolic variables, which focused on four cardiometabolic variables, these were postprandial responses of glucose, insulin, cortisol, and subjective appetite variables. A randomized cross-over human study in 20 healthy subjects was conducted, in which subjects were assigned to consume test or reference breakfasts in random order. Test breakfasts consisted of white wheat bread (WWB) with spreads consisted of oat lipids containing 15 g polar lipids (OL), rapeseed oils (Raps), and a mixture of oat lipids (8.3... (More)
- Consumers are becoming interested in oats as a healthy food. Several studies have investigated the impact of oats components on human metabolism. The purpose of this project is to study the influence of oat polar lipids on human cardiometabolic variables, which focused on four cardiometabolic variables, these were postprandial responses of glucose, insulin, cortisol, and subjective appetite variables. A randomized cross-over human study in 20 healthy subjects was conducted, in which subjects were assigned to consume test or reference breakfasts in random order. Test breakfasts consisted of white wheat bread (WWB) with spreads consisted of oat lipids containing 15 g polar lipids (OL), rapeseed oils (Raps), and a mixture of oat lipids (8.3 g) and rapeseeds oil (Mix). A plain WWB without lipids was included as a reference breakfast. All test breakfast contained similar amounts of lipids. Cardiometabolic test variables were determined at different times postprandially. The results showed that OL resulted in the lowest increase in concentrations of glucose and insulin after breakfast. The effect of oat polar lipids on cortisol wasn't statistically significant, however, this could be due to too few test subjects included in the study. Three appetite related variables: fullness, hunger, and desire to eat, were also measured. OL resulted in the lowest ratings of hunger and desire to eat. It is concluded that oat polar lipids are effective in decreasing postprandial blood glucose and insulin concentrations. At the same time, OL also has a beneficial effect on appetite variables, indicated by increasing satiety and decreasing hunger. The results provide information regarding oat polar lipids as possible new bioactive compounds with preventive potential against obesity and type 2 diabetes. (Less)
- Popular Abstract
- People’s health is negatively affected due to excessive consumption of processed foods and a sedentary lifestyle, which result in an increase of the proportion of people suffering from metabolic syndromes, as well as the risk of cardiometabolic related diseases. Dietary intervention is one of the most economical and convenient methods to reduce the risk of illness, since diet is an indispensable part of daily life. Oils are a common and essential part of the daily diet, so it is feasible to keep health by eating healthier oils, such as oat polar lipids. Oat polar lipids are extracted from oats. It has great potential to become an emerging healthy food, there is not much research on the effects of oat lipids on the human body. Therefore,... (More)
- People’s health is negatively affected due to excessive consumption of processed foods and a sedentary lifestyle, which result in an increase of the proportion of people suffering from metabolic syndromes, as well as the risk of cardiometabolic related diseases. Dietary intervention is one of the most economical and convenient methods to reduce the risk of illness, since diet is an indispensable part of daily life. Oils are a common and essential part of the daily diet, so it is feasible to keep health by eating healthier oils, such as oat polar lipids. Oat polar lipids are extracted from oats. It has great potential to become an emerging healthy food, there is not much research on the effects of oat lipids on the human body. Therefore, the aim of this project was to study the influence of oat polar lipids on human cardiometabolic variables, including four sections: postprandial glucose response, insulin, cortisol, and subjective appetite variables.
A human study in 20 healthy subjects was conducted for investigation. Three test breakfasts (oat polar lipids, rapeseed oils and the mixture of oat polar lipids and rapeseed oils) and a reference breakfast (white wheat bread) were prepared for them. The human study lasted 330 minutes. At 8:00 am, the subjects came to the laboratory at fasting state. Firstly, fasting blood glucose was measured through fingertip blood collection and extra blood samples were collected for insulin and cortisol analysis. After that, they got one of the test breakfasts or the reference, which was consumed in around 12 min. Then their blood glucose was tested repeatedly, and blood samples were collected. After 210 minutes, the subjects ate a standardized lunch (meatball sandwich). Then the measurement of blood glucose and collection of blood samples were continued until the end of the test day. At the same time, the subjects needed to fill out the appetite survey based on their true feelings, which contains three variables: fullness, hunger and desire to eat.
The results showed that the effect of oat polar lipids in lowering blood glucose was significantly better than the other oils and it also increased satiety and reduced hunger compared with other test products. Therefore, can be recommended to people with metabolic syndrome can supplement their diet with oat polar lipids, which will help them relieve symptoms. Healthy people can also be recommended to consume oat polar lipids to reduce the risk of obesity and cardiovascular disease and other related diseases. However, people have to be aware of that irrespective of the type of oil, any oil that is consumed in excess may result in weight gain. (Less)
Please use this url to cite or link to this publication:
http://lup.lub.lu.se/student-papers/record/9056991
- author
- Wang, Yi LU
- supervisor
- organization
- course
- KNLM01 20211
- year
- 2021
- type
- H2 - Master's Degree (Two Years)
- subject
- keywords
- oat polar lipids, bio-actives, metabolic diseases, applied nutrition, food chemistry
- language
- English
- id
- 9056991
- date added to LUP
- 2021-06-29 10:31:40
- date last changed
- 2021-10-01 03:41:07
@misc{9056991,
abstract = {{Consumers are becoming interested in oats as a healthy food. Several studies have investigated the impact of oats components on human metabolism. The purpose of this project is to study the influence of oat polar lipids on human cardiometabolic variables, which focused on four cardiometabolic variables, these were postprandial responses of glucose, insulin, cortisol, and subjective appetite variables. A randomized cross-over human study in 20 healthy subjects was conducted, in which subjects were assigned to consume test or reference breakfasts in random order. Test breakfasts consisted of white wheat bread (WWB) with spreads consisted of oat lipids containing 15 g polar lipids (OL), rapeseed oils (Raps), and a mixture of oat lipids (8.3 g) and rapeseeds oil (Mix). A plain WWB without lipids was included as a reference breakfast. All test breakfast contained similar amounts of lipids. Cardiometabolic test variables were determined at different times postprandially. The results showed that OL resulted in the lowest increase in concentrations of glucose and insulin after breakfast. The effect of oat polar lipids on cortisol wasn't statistically significant, however, this could be due to too few test subjects included in the study. Three appetite related variables: fullness, hunger, and desire to eat, were also measured. OL resulted in the lowest ratings of hunger and desire to eat. It is concluded that oat polar lipids are effective in decreasing postprandial blood glucose and insulin concentrations. At the same time, OL also has a beneficial effect on appetite variables, indicated by increasing satiety and decreasing hunger. The results provide information regarding oat polar lipids as possible new bioactive compounds with preventive potential against obesity and type 2 diabetes.}},
author = {{Wang, Yi}},
language = {{eng}},
note = {{Student Paper}},
title = {{Effect of Oat Bio-actives on Cardiometabolic Related Variables in Humans}},
year = {{2021}},
}