Chemotherapy in Ewing's sarcoma. The Scandinavian Sarcoma Group experience
(1999) In Acta Orthopaedica Scandinavica. Supplementum 70(285). p.69-73- Abstract
- During the past 15 years the Scandinavian Sarcoma Group has treated 140 patients with Ewing's sarcoma. Two protocols have been used. SSG IV included 52 patients between 1984 and 1990 and SSG IX, 88 patients since 1990. After 5 years of treatment, local recurrences occurred in 19% of the patients (M0 + M1) in the SSG IV group and 10% in the SSG IX group. Distant metastases developed in 57% of the M0-patients in the SSG IV group and in 33% in the SSG IX group. Tumor-related survival (overall) of M0-patients was 49% in SSG IV and 70% in SSG IX, and the metastasis-free survival rate 45% and 58%, respectively. Patients having a localized extremity tumor had a survival rate of 90% (SSG IX). In both treatment groups, good responders to... (More)
- During the past 15 years the Scandinavian Sarcoma Group has treated 140 patients with Ewing's sarcoma. Two protocols have been used. SSG IV included 52 patients between 1984 and 1990 and SSG IX, 88 patients since 1990. After 5 years of treatment, local recurrences occurred in 19% of the patients (M0 + M1) in the SSG IV group and 10% in the SSG IX group. Distant metastases developed in 57% of the M0-patients in the SSG IV group and in 33% in the SSG IX group. Tumor-related survival (overall) of M0-patients was 49% in SSG IV and 70% in SSG IX, and the metastasis-free survival rate 45% and 58%, respectively. Patients having a localized extremity tumor had a survival rate of 90% (SSG IX). In both treatment groups, good responders to chemotherapy had a better survival rate than poor ones (SSG IV, p < 0.02, GI-II vs. G II-IV and SSG IX, p < 0.003, GI-III vs. G IV). In conclusions local control and survival rates were better with SSG IX than SSG IV. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1115411
- author
- Elomaa, I ; Blomqvist, C ; Saeter, G ; Nilbert, Mef LU ; Monge, O R ; Wiebe, Thomas LU and Alvegård, Thor LU
- organization
- publishing date
- 1999
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Orthopaedica Scandinavica. Supplementum
- volume
- 70
- issue
- 285
- pages
- 69 - 73
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:10429626
- scopus:0032769533
- ISSN
- 0300-8827
- language
- English
- LU publication?
- yes
- id
- 96bc97e6-897d-4bfb-8ac4-1a052d7af760 (old id 1115411)
- date added to LUP
- 2016-04-01 15:31:14
- date last changed
- 2022-01-28 05:43:38
@article{96bc97e6-897d-4bfb-8ac4-1a052d7af760,
abstract = {{During the past 15 years the Scandinavian Sarcoma Group has treated 140 patients with Ewing's sarcoma. Two protocols have been used. SSG IV included 52 patients between 1984 and 1990 and SSG IX, 88 patients since 1990. After 5 years of treatment, local recurrences occurred in 19% of the patients (M0 + M1) in the SSG IV group and 10% in the SSG IX group. Distant metastases developed in 57% of the M0-patients in the SSG IV group and in 33% in the SSG IX group. Tumor-related survival (overall) of M0-patients was 49% in SSG IV and 70% in SSG IX, and the metastasis-free survival rate 45% and 58%, respectively. Patients having a localized extremity tumor had a survival rate of 90% (SSG IX). In both treatment groups, good responders to chemotherapy had a better survival rate than poor ones (SSG IV, p < 0.02, GI-II vs. G II-IV and SSG IX, p < 0.003, GI-III vs. G IV). In conclusions local control and survival rates were better with SSG IX than SSG IV.}},
author = {{Elomaa, I and Blomqvist, C and Saeter, G and Nilbert, Mef and Monge, O R and Wiebe, Thomas and Alvegård, Thor}},
issn = {{0300-8827}},
language = {{eng}},
number = {{285}},
pages = {{69--73}},
publisher = {{Taylor & Francis}},
series = {{Acta Orthopaedica Scandinavica. Supplementum}},
title = {{Chemotherapy in Ewing's sarcoma. The Scandinavian Sarcoma Group experience}},
volume = {{70}},
year = {{1999}},
}