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A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter

Gustafsson, Mattias LU and von Wachenfeldt, Claes LU (2001) In FEMS Microbiology Letters 199(2). p.197-202
Abstract
In this work we present evidence for a novel diffusible extracellular factor that modulates gene expression in Bacillus subtilis. The factor was found when studying the regulation of the fatR-cyp102A3 operon. In a Spo0A(-) mutant expression of the fatR-cyp102A3 operon was almost abolished. The fatR-cyp102A3 expression defect of a Spo0A(-) mutant could be overcome either by a mutation in the abrB gene or by a diffusible substance excreted by wild-type, abrB mutant and abrB-spo0A double mutant strains.
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cytochrome P450, AbrB, FatR, Bacillus subtilis
in
FEMS Microbiology Letters
volume
199
issue
2
pages
197 - 202
publisher
Oxford University Press
external identifiers
  • pmid:11377867
  • scopus:0035972878
ISSN
1574-6968
DOI
10.1016/S0378-1097(01)00177-X
language
English
LU publication?
yes
id
01a7e67e-cf02-4154-92cd-319c308c5c75 (old id 1121791)
date added to LUP
2016-04-01 16:58:52
date last changed
2022-01-28 23:28:35
@article{01a7e67e-cf02-4154-92cd-319c308c5c75,
  abstract     = {{In this work we present evidence for a novel diffusible extracellular factor that modulates gene expression in Bacillus subtilis. The factor was found when studying the regulation of the fatR-cyp102A3 operon. In a Spo0A(-) mutant expression of the fatR-cyp102A3 operon was almost abolished. The fatR-cyp102A3 expression defect of a Spo0A(-) mutant could be overcome either by a mutation in the abrB gene or by a diffusible substance excreted by wild-type, abrB mutant and abrB-spo0A double mutant strains.}},
  author       = {{Gustafsson, Mattias and von Wachenfeldt, Claes}},
  issn         = {{1574-6968}},
  keywords     = {{Cytochrome P450; AbrB; FatR; Bacillus subtilis}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{197--202}},
  publisher    = {{Oxford University Press}},
  series       = {{FEMS Microbiology Letters}},
  title        = {{A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter}},
  url          = {{http://dx.doi.org/10.1016/S0378-1097(01)00177-X}},
  doi          = {{10.1016/S0378-1097(01)00177-X}},
  volume       = {{199}},
  year         = {{2001}},
}