Use of nonlinear upconverting nanoparticles provide increased spatial resolution in fluorescence diffuse imaging
(2010) In Optics Letters 35(16). p.2789-2791- Abstract
- Fluorescence diffuse imaging suffers from limited spatial resolution. In this
letter, we report a scanning imaging approach to increase the resolution of
fluorescence diffuse imaging using nonlinear fluorophores. The resolution of
a linear flurophore was compared with nonlinear upconverting nanoparticles
(NaYF4 : Yb3+ /Tm3+ ) in a tissue phantom. A resolution improvement of a
factor of 1.3 was found experimentally. Simulations suggested a maximum
resolution improvement of a factor of 1.45. Usage of nonlinear fluorophores
is a promising method for increasing the spatial resolution in fluorescence
diffuse imaging. c 2010 Optical Society of America
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1659154
- author
- Svenmarker, Pontus LU ; Xu, Can LU and Andersson-Engels, Stefan LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Optics Letters
- volume
- 35
- issue
- 16
- pages
- 2789 - 2791
- publisher
- Optical Society of America
- external identifiers
-
- wos:000281062400041
- scopus:77955889469
- ISSN
- 0146-9592
- DOI
- 10.1364/OL.35.002789
- language
- English
- LU publication?
- yes
- id
- 27f800a3-1c18-4612-82f8-5d1bebacc508 (old id 1659154)
- alternative location
- http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-35-11-1740
- date added to LUP
- 2016-04-01 14:12:18
- date last changed
- 2022-01-27 23:23:21
@article{27f800a3-1c18-4612-82f8-5d1bebacc508, abstract = {{Fluorescence diffuse imaging suffers from limited spatial resolution. In this<br/><br> letter, we report a scanning imaging approach to increase the resolution of<br/><br> fluorescence diffuse imaging using nonlinear fluorophores. The resolution of<br/><br> a linear flurophore was compared with nonlinear upconverting nanoparticles<br/><br> (NaYF4 : Yb3+ /Tm3+ ) in a tissue phantom. A resolution improvement of a<br/><br> factor of 1.3 was found experimentally. Simulations suggested a maximum<br/><br> resolution improvement of a factor of 1.45. Usage of nonlinear fluorophores<br/><br> is a promising method for increasing the spatial resolution in fluorescence<br/><br> diffuse imaging. c 2010 Optical Society of America}}, author = {{Svenmarker, Pontus and Xu, Can and Andersson-Engels, Stefan}}, issn = {{0146-9592}}, language = {{eng}}, number = {{16}}, pages = {{2789--2791}}, publisher = {{Optical Society of America}}, series = {{Optics Letters}}, title = {{Use of nonlinear upconverting nanoparticles provide increased spatial resolution in fluorescence diffuse imaging}}, url = {{https://lup.lub.lu.se/search/files/3842359/2370793.pdf}}, doi = {{10.1364/OL.35.002789}}, volume = {{35}}, year = {{2010}}, }