Evaluation of depolarization changes during acute myocardial ischemia by analysis of QRS slopes.
(2011) In Journal of Electrocardiology 44(4). p.416-424- Abstract
- OBJECTIVE: This study evaluates depolarization changes in acute myocardial ischemia by analysis of QRS slopes. METHODS: In 38 patients undergoing elective percutaneous coronary intervention, changes in upward slope between Q and R waves and downward slope between R and S waves (DS) were analyzed. In leads V1 to V3, upward slope of the S wave was additionally analyzed. Ischemia was quantified by myocardial scintigraphy. Also, conventional QRS and ST measures were determined. RESULTS: QRS slope changes correlated significantly with ischemia (for DS: r = 0.71, P < .0001 for extent, and r = 0.73, P < .0001 for severity). Best corresponding correlation for conventional electrocardiogram parameters was the sum of R-wave amplitude change (r... (More)
- OBJECTIVE: This study evaluates depolarization changes in acute myocardial ischemia by analysis of QRS slopes. METHODS: In 38 patients undergoing elective percutaneous coronary intervention, changes in upward slope between Q and R waves and downward slope between R and S waves (DS) were analyzed. In leads V1 to V3, upward slope of the S wave was additionally analyzed. Ischemia was quantified by myocardial scintigraphy. Also, conventional QRS and ST measures were determined. RESULTS: QRS slope changes correlated significantly with ischemia (for DS: r = 0.71, P < .0001 for extent, and r = 0.73, P < .0001 for severity). Best corresponding correlation for conventional electrocardiogram parameters was the sum of R-wave amplitude change (r = 0.63, P < .0001; r = 0.60, P < .0001) and the sum of ST-segment elevation (r = 0.67, P < .0001; r = 0.73, P < .0001). Prediction of extent and severity of ischemia increased by 12.2% and 7.1% by adding DS to ST. CONCLUSIONS: The downward slope between R and S waves correlates with ischemia and could have potential value in risk stratification in acute ischemia in addition to ST-T analysis. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1936650
- author
- Ringborn, Michael LU ; Romero, Daniel ; Pueyo, Esther ; Pahlm, Olle LU ; Wagner, Galen S ; Laguna, Pablo and Platonov, Pyotr LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Electrocardiology
- volume
- 44
- issue
- 4
- pages
- 416 - 424
- publisher
- Elsevier
- external identifiers
-
- wos:000292577600005
- pmid:21524754
- scopus:79959702194
- pmid:21524754
- ISSN
- 1532-8430
- DOI
- 10.1016/j.jelectrocard.2011.03.005
- language
- English
- LU publication?
- yes
- id
- 08fc20ed-e677-47bc-bf47-d2d2372d3935 (old id 1936650)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21524754?dopt=Abstract
- date added to LUP
- 2016-04-01 10:20:23
- date last changed
- 2022-03-04 18:35:03
@article{08fc20ed-e677-47bc-bf47-d2d2372d3935, abstract = {{OBJECTIVE: This study evaluates depolarization changes in acute myocardial ischemia by analysis of QRS slopes. METHODS: In 38 patients undergoing elective percutaneous coronary intervention, changes in upward slope between Q and R waves and downward slope between R and S waves (DS) were analyzed. In leads V1 to V3, upward slope of the S wave was additionally analyzed. Ischemia was quantified by myocardial scintigraphy. Also, conventional QRS and ST measures were determined. RESULTS: QRS slope changes correlated significantly with ischemia (for DS: r = 0.71, P < .0001 for extent, and r = 0.73, P < .0001 for severity). Best corresponding correlation for conventional electrocardiogram parameters was the sum of R-wave amplitude change (r = 0.63, P < .0001; r = 0.60, P < .0001) and the sum of ST-segment elevation (r = 0.67, P < .0001; r = 0.73, P < .0001). Prediction of extent and severity of ischemia increased by 12.2% and 7.1% by adding DS to ST. CONCLUSIONS: The downward slope between R and S waves correlates with ischemia and could have potential value in risk stratification in acute ischemia in addition to ST-T analysis.}}, author = {{Ringborn, Michael and Romero, Daniel and Pueyo, Esther and Pahlm, Olle and Wagner, Galen S and Laguna, Pablo and Platonov, Pyotr}}, issn = {{1532-8430}}, language = {{eng}}, number = {{4}}, pages = {{416--424}}, publisher = {{Elsevier}}, series = {{Journal of Electrocardiology}}, title = {{Evaluation of depolarization changes during acute myocardial ischemia by analysis of QRS slopes.}}, url = {{https://lup.lub.lu.se/search/files/1760796/2171957.pdf}}, doi = {{10.1016/j.jelectrocard.2011.03.005}}, volume = {{44}}, year = {{2011}}, }