Older Adults' Medication Use 6 Months Before and After Hip Fracture: A Population-Based Cohort Study.
(2011) In Journal of the American Geriatrics Society 59. p.863-868- Abstract
- OBJECTIVES: To study changes in use of fall-risk increasing drugs (FRIDs) and bone density-related medication in participants with hip fracture before and after the fracture and to analyze differences between five healthcare districts. DESIGN: Population-based cohort study. SETTING: Data retrieved from two national databases PARTICIPANTS: All 2,043 people with hip fracture aged 60 and older in a Swedish county in 2006. MEASUREMENTS: Changes in FRIDs and bone-active medications prescribed within 6 months before and 6 months after hip fracture and differences between health care districts. RESULTS: Before hip fracture, 1,308 participants (67.7%) received any FRIDs or combinations; after fracture, 97.7% were treated. Polypharmacy (≥5 drugs)... (More)
- OBJECTIVES: To study changes in use of fall-risk increasing drugs (FRIDs) and bone density-related medication in participants with hip fracture before and after the fracture and to analyze differences between five healthcare districts. DESIGN: Population-based cohort study. SETTING: Data retrieved from two national databases PARTICIPANTS: All 2,043 people with hip fracture aged 60 and older in a Swedish county in 2006. MEASUREMENTS: Changes in FRIDs and bone-active medications prescribed within 6 months before and 6 months after hip fracture and differences between health care districts. RESULTS: Before hip fracture, 1,308 participants (67.7%) received any FRIDs or combinations; after fracture, 97.7% were treated. Polypharmacy (≥5 drugs) increased 39.3%, excessive polypharmacy (≥10 drugs) increased 36.4%, and use of three or more psychotropic drugs increased 8.6%. After fracture, the use of all analyzed drugs including psychotropic, cardiovascular, opioid, and anticholinergic drugs increased significantly (P<.001). Treatment with calcium and vitamin D increased from 9% before to 27.7% after and with bisphosphonates from 3.5% to 7.6%. Variations in postfracture prescribing between the five health care districts were observed regarding opioids (range 85-64%), bisphosphonates (range 20-4%), and calcium and vitamin D (72-13%) (P<.001, for all comparisons). CONCLUSION: Two-thirds of participants with hip fracture were prescribed FRIDs before fracture, and the number increased significantly after fracture. Significant variations between healthcare districts in treating osteoporosis and pain were evident; geriatric support could be a contributing factor to the greater treatment in two districts. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1936772
- author
- Kragh Ekstam, Annika LU ; Elmståhl, Sölve LU and Atroshi, Isam LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the American Geriatrics Society
- volume
- 59
- pages
- 863 - 868
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000290578700012
- pmid:21517788
- scopus:79956021641
- pmid:21517788
- ISSN
- 0002-8614
- DOI
- 10.1111/j.1532-5415.2011.03372.x
- language
- English
- LU publication?
- yes
- id
- e2af1dfe-08a9-4c80-a653-a6285330273d (old id 1936772)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21517788?dopt=Abstract
- date added to LUP
- 2016-04-04 07:10:15
- date last changed
- 2022-01-29 01:49:35
@article{e2af1dfe-08a9-4c80-a653-a6285330273d, abstract = {{OBJECTIVES: To study changes in use of fall-risk increasing drugs (FRIDs) and bone density-related medication in participants with hip fracture before and after the fracture and to analyze differences between five healthcare districts. DESIGN: Population-based cohort study. SETTING: Data retrieved from two national databases PARTICIPANTS: All 2,043 people with hip fracture aged 60 and older in a Swedish county in 2006. MEASUREMENTS: Changes in FRIDs and bone-active medications prescribed within 6 months before and 6 months after hip fracture and differences between health care districts. RESULTS: Before hip fracture, 1,308 participants (67.7%) received any FRIDs or combinations; after fracture, 97.7% were treated. Polypharmacy (≥5 drugs) increased 39.3%, excessive polypharmacy (≥10 drugs) increased 36.4%, and use of three or more psychotropic drugs increased 8.6%. After fracture, the use of all analyzed drugs including psychotropic, cardiovascular, opioid, and anticholinergic drugs increased significantly (P<.001). Treatment with calcium and vitamin D increased from 9% before to 27.7% after and with bisphosphonates from 3.5% to 7.6%. Variations in postfracture prescribing between the five health care districts were observed regarding opioids (range 85-64%), bisphosphonates (range 20-4%), and calcium and vitamin D (72-13%) (P<.001, for all comparisons). CONCLUSION: Two-thirds of participants with hip fracture were prescribed FRIDs before fracture, and the number increased significantly after fracture. Significant variations between healthcare districts in treating osteoporosis and pain were evident; geriatric support could be a contributing factor to the greater treatment in two districts.}}, author = {{Kragh Ekstam, Annika and Elmståhl, Sölve and Atroshi, Isam}}, issn = {{0002-8614}}, language = {{eng}}, pages = {{863--868}}, publisher = {{Wiley-Blackwell}}, series = {{Journal of the American Geriatrics Society}}, title = {{Older Adults' Medication Use 6 Months Before and After Hip Fracture: A Population-Based Cohort Study.}}, url = {{http://dx.doi.org/10.1111/j.1532-5415.2011.03372.x}}, doi = {{10.1111/j.1532-5415.2011.03372.x}}, volume = {{59}}, year = {{2011}}, }