Quantification and visualization of cardiovascular 4D velocity mapping accelerated with parallel imaging or k-t BLAST: head to head comparison and validation at 1.5 T and 3 T
Carlsson, Marcus LU ; Töger, Johannes LU ; Kanski, Mikael LU ; Markenroth Bloch, Karin LU
; Ståhlberg, Freddy
LU
; Heiberg, Einar
LU
and Arheden, Håkan
LU
(2011)
In Journal of Cardiovascular Magnetic Resonance
13(55).
- Abstract
- Background: Three-dimensional time-resolved (4D) phase-contrast (PC) CMR can visualize and quantify cardiovascular flow but is hampered by long acquisition times. Acceleration with SENSE or k-t BLAST are two possibilities but results on validation are lacking, especially at 3 T. The aim of this study was therefore to validate quantitative in vivo cardiac 4D-acquisitions accelerated with parallel imaging and k-t BLAST at 1.5 T and 3 T with 2D-flow as the reference and to investigate if field strengths and type of acceleration have major effects on intracardiac flow visualization. Methods: The local ethical committee approved the study. 13 healthy volunteers were scanned at both 1.5 T and 3 T in random order with 2D-flow of the aorta and... (More)
- Background: Three-dimensional time-resolved (4D) phase-contrast (PC) CMR can visualize and quantify cardiovascular flow but is hampered by long acquisition times. Acceleration with SENSE or k-t BLAST are two possibilities but results on validation are lacking, especially at 3 T. The aim of this study was therefore to validate quantitative in vivo cardiac 4D-acquisitions accelerated with parallel imaging and k-t BLAST at 1.5 T and 3 T with 2D-flow as the reference and to investigate if field strengths and type of acceleration have major effects on intracardiac flow visualization. Methods: The local ethical committee approved the study. 13 healthy volunteers were scanned at both 1.5 T and 3 T in random order with 2D-flow of the aorta and main pulmonary artery and two 4D-flow sequences of the heart accelerated with SENSE and k-t BLAST respectively. 2D-image planes were reconstructed at the aortic and pulmonary outflow. Flow curves were calculated and peak flows and stroke volumes (SV) compared to the results from 2D-flow acquisitions. Intra-cardiac flow was visualized using particle tracing and image quality based on the flow patterns of the particles was graded using a four-point scale. Results: Good accuracy of SV quantification was found using 3 T 4D-SENSE (r(2) = 0.86, -0.7 +/- 7.6%) and although a larger bias was found on 1.5 T (r(2) = 0.71, -3.6 +/- 14.8%), the difference was not significant (p = 0.46). Accuracy of 4D k-t BLAST for SV was lower (p < 0.01) on 1.5 T (r(2) = 0.65, -15.6 +/- 13.7%) compared to 3 T (r(2) = 0.64, -4.6 +/- 10.0%). Peak flow was lower with 4D-SENSE at both 3 T and 1.5 T compared to 2D-flow (p < 0.01) and even lower with 4D k-t BLAST at both scanners (p < 0.01). Intracardiac flow visualization did not differ between 1.5 T and 3 T (p = 0.09) or between 4D-SENSE or 4D k-t BLAST (p = 0.85). Conclusions: The present study showed that quantitative 4D flow accelerated with SENSE has good accuracy at 3 T and compares favourably to 1.5 T. 4D flow accelerated with k-t BLAST underestimate flow velocities and thereby yield too high bias for intra-cardiac quantitative in vivo use at the present time. For intra-cardiac 4D-flow visualization, however, 1.5 T and 3 T as well as SENSE or k-t BLAST can be used with similar quality. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2254413
- author
- Carlsson, Marcus
LU
; Töger, Johannes
LU
; Kanski, Mikael
LU
; Markenroth Bloch, Karin
LU
; Ståhlberg, Freddy
LU
; Heiberg, Einar
LU
and Arheden, Håkan
LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Cardiovascular Magnetic Resonance
- volume
- 13
- issue
- 55
- publisher
- BioMed Central (BMC)
- external identifiers
-
- wos:000296842200001
- scopus:84857015934
- pmid:21970399
- ISSN
- 1097-6647
- DOI
- 10.1186/1532-429X-13-55
- language
- English
- LU publication?
- yes
- id
- 8bea61bb-ffcd-45ea-86a5-8f594e3a8c80 (old id 2254413)
- date added to LUP
- 2016-04-01 10:23:46
- date last changed
- 2022-04-27 21:40:44
@article{8bea61bb-ffcd-45ea-86a5-8f594e3a8c80,
abstract = {{Background: Three-dimensional time-resolved (4D) phase-contrast (PC) CMR can visualize and quantify cardiovascular flow but is hampered by long acquisition times. Acceleration with SENSE or k-t BLAST are two possibilities but results on validation are lacking, especially at 3 T. The aim of this study was therefore to validate quantitative in vivo cardiac 4D-acquisitions accelerated with parallel imaging and k-t BLAST at 1.5 T and 3 T with 2D-flow as the reference and to investigate if field strengths and type of acceleration have major effects on intracardiac flow visualization. Methods: The local ethical committee approved the study. 13 healthy volunteers were scanned at both 1.5 T and 3 T in random order with 2D-flow of the aorta and main pulmonary artery and two 4D-flow sequences of the heart accelerated with SENSE and k-t BLAST respectively. 2D-image planes were reconstructed at the aortic and pulmonary outflow. Flow curves were calculated and peak flows and stroke volumes (SV) compared to the results from 2D-flow acquisitions. Intra-cardiac flow was visualized using particle tracing and image quality based on the flow patterns of the particles was graded using a four-point scale. Results: Good accuracy of SV quantification was found using 3 T 4D-SENSE (r(2) = 0.86, -0.7 +/- 7.6%) and although a larger bias was found on 1.5 T (r(2) = 0.71, -3.6 +/- 14.8%), the difference was not significant (p = 0.46). Accuracy of 4D k-t BLAST for SV was lower (p < 0.01) on 1.5 T (r(2) = 0.65, -15.6 +/- 13.7%) compared to 3 T (r(2) = 0.64, -4.6 +/- 10.0%). Peak flow was lower with 4D-SENSE at both 3 T and 1.5 T compared to 2D-flow (p < 0.01) and even lower with 4D k-t BLAST at both scanners (p < 0.01). Intracardiac flow visualization did not differ between 1.5 T and 3 T (p = 0.09) or between 4D-SENSE or 4D k-t BLAST (p = 0.85). Conclusions: The present study showed that quantitative 4D flow accelerated with SENSE has good accuracy at 3 T and compares favourably to 1.5 T. 4D flow accelerated with k-t BLAST underestimate flow velocities and thereby yield too high bias for intra-cardiac quantitative in vivo use at the present time. For intra-cardiac 4D-flow visualization, however, 1.5 T and 3 T as well as SENSE or k-t BLAST can be used with similar quality.}},
author = {{Carlsson, Marcus and Töger, Johannes and Kanski, Mikael and Markenroth Bloch, Karin and Ståhlberg, Freddy and Heiberg, Einar and Arheden, Håkan}},
issn = {{1097-6647}},
language = {{eng}},
number = {{55}},
publisher = {{BioMed Central (BMC)}},
series = {{Journal of Cardiovascular Magnetic Resonance}},
title = {{Quantification and visualization of cardiovascular 4D velocity mapping accelerated with parallel imaging or k-t BLAST: head to head comparison and validation at 1.5 T and 3 T}},
url = {{https://lup.lub.lu.se/search/files/1809515/2369123.pdf}},
doi = {{10.1186/1532-429X-13-55}},
volume = {{13}},
year = {{2011}},
}