Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy.
(2013) In Psychoneuroendocrinology 38(6). p.842-852- Abstract
- CONTEXT: The psychosocial health and working capacity in hypopituitary patients receiving long-term growth hormone (GH) therapy are unknown. OBJECTIVE: Psychosocial health and levels of employment were compared between GH deficient (GHD) patients on long-term replacement and the general population. DESIGN AND PARTICIPANTS: In a Swedish nationwide study, 851 GHD patients [101 childhood onset (CO) and 750 adult onset (AO)] and 2622 population controls answered a questionnaire regarding current living, employment and educational level, alcohol consumption and smoking habits. The median time on GH therapy for both men and women with CO GHD was 9 years and for AO GHD 6 years, respectively. RESULTS: As compared to the controls, the GHD patients... (More)
- CONTEXT: The psychosocial health and working capacity in hypopituitary patients receiving long-term growth hormone (GH) therapy are unknown. OBJECTIVE: Psychosocial health and levels of employment were compared between GH deficient (GHD) patients on long-term replacement and the general population. DESIGN AND PARTICIPANTS: In a Swedish nationwide study, 851 GHD patients [101 childhood onset (CO) and 750 adult onset (AO)] and 2622 population controls answered a questionnaire regarding current living, employment and educational level, alcohol consumption and smoking habits. The median time on GH therapy for both men and women with CO GHD was 9 years and for AO GHD 6 years, respectively. RESULTS: As compared to the controls, the GHD patients were less often working full time, more often on sick leave/disability pension, and to a larger extent alcohol abstainers and never smokers (all; P<0.05). Predominantly CO GHD women and men, but to some extent also AO GHD women and men, lived less frequently with a partner and more often with their parents. Particularly AO GHD craniopharyngioma women used more antidepressants, while AO GHD men with a craniopharyngioma used more analgesics. CONCLUSIONS: A working capacity to the level of the general population was not achieved among hypopituitary patients, although receiving long-term GH therapy. Patients were less likely to use alcohol and tobacco. The CO GHD population lived a less independent life. (Less)
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- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Psychoneuroendocrinology
- volume
- 38
- issue
- 6
- pages
- 842 - 852
- publisher
- Elsevier
- external identifiers
-
- wos:000319540000011
- pmid:23040973
- scopus:84877065154
- pmid:23040973
- ISSN
- 1873-3360
- DOI
- 10.1016/j.psyneuen.2012.09.008
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Department of Electroscience (011041000), Division of Occupational and Environmental Medicine (013078001), Medicine (Lund) (013230025), Paediatric Endocrinology Research Group (013243010)
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- 9c481572-4325-4b30-ba46-a78b83fa1d88 (old id 3161027)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23040973?dopt=Abstract
- date added to LUP
- 2016-04-01 10:45:55
- date last changed
- 2024-01-07 00:44:00
@article{9c481572-4325-4b30-ba46-a78b83fa1d88, abstract = {{CONTEXT: The psychosocial health and working capacity in hypopituitary patients receiving long-term growth hormone (GH) therapy are unknown. OBJECTIVE: Psychosocial health and levels of employment were compared between GH deficient (GHD) patients on long-term replacement and the general population. DESIGN AND PARTICIPANTS: In a Swedish nationwide study, 851 GHD patients [101 childhood onset (CO) and 750 adult onset (AO)] and 2622 population controls answered a questionnaire regarding current living, employment and educational level, alcohol consumption and smoking habits. The median time on GH therapy for both men and women with CO GHD was 9 years and for AO GHD 6 years, respectively. RESULTS: As compared to the controls, the GHD patients were less often working full time, more often on sick leave/disability pension, and to a larger extent alcohol abstainers and never smokers (all; P<0.05). Predominantly CO GHD women and men, but to some extent also AO GHD women and men, lived less frequently with a partner and more often with their parents. Particularly AO GHD craniopharyngioma women used more antidepressants, while AO GHD men with a craniopharyngioma used more analgesics. CONCLUSIONS: A working capacity to the level of the general population was not achieved among hypopituitary patients, although receiving long-term GH therapy. Patients were less likely to use alcohol and tobacco. The CO GHD population lived a less independent life.}}, author = {{Holmer, Helene and Svensson, Johan and Rylander, Lars and Johannsson, Gudmundur and Rosén, Thord and Bengtsson, Bengt A and Thorén, Marja and Höybye, Charlotte and Degerblad, Marie and Bramnert, Margareta and Hägg, Erik and Engström, Britt Edén and Ekman, Bertil and Erfurth, Eva Marie}}, issn = {{1873-3360}}, language = {{eng}}, number = {{6}}, pages = {{842--852}}, publisher = {{Elsevier}}, series = {{Psychoneuroendocrinology}}, title = {{Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy.}}, url = {{http://dx.doi.org/10.1016/j.psyneuen.2012.09.008}}, doi = {{10.1016/j.psyneuen.2012.09.008}}, volume = {{38}}, year = {{2013}}, }