Characterization of Hox genes in the bichir, Polypterus palmas
(2002) In Journal of Experimental Zoology 294(2). p.107-111- Abstract
- It has been suggested that the increase in the number of Hox genes may have been one of the key events in vertebrate evolution. Invertebrates have one Hox cluster, while mammals have four. Interestingly, the number of Hox gene clusters is greater in the teleost fishes, zebrafish and medaka, than in mouse and human. The greater number of Hox clusters in the teleosts suggests that Hox gene duplication events have occurred during the radiation of ray-finned fishes. The question is when the Hox gene duplication event(s) that lead to seven Hox clusters in the teleosts actually occurred. We have addressed this question by studying the Hox genes in the bichir, Polypterus palmas. A preliminary PCR-estimation of the number of Hox genes suggests... (More)
- It has been suggested that the increase in the number of Hox genes may have been one of the key events in vertebrate evolution. Invertebrates have one Hox cluster, while mammals have four. Interestingly, the number of Hox gene clusters is greater in the teleost fishes, zebrafish and medaka, than in mouse and human. The greater number of Hox clusters in the teleosts suggests that Hox gene duplication events have occurred during the radiation of ray-finned fishes. The question is when the Hox gene duplication event(s) that lead to seven Hox clusters in the teleosts actually occurred. We have addressed this question by studying the Hox genes in the bichir, Polypterus palmas. A preliminary PCR-estimation of the number of Hox genes suggests that Polypterus has five different Hox9 cognate group genes, which may be an indication of more than four Hox clusters in the bichir. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/332290
- author
- Ledje, Christina LU ; Kim, Chang-aeB and Ruddle, Francis H
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Experimental Zoology
- volume
- 294
- issue
- 2
- pages
- 107 - 111
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000177187600003
- pmid:12210111
- scopus:0037103614
- ISSN
- 0022-104X
- DOI
- 10.1002/jez.10152
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Genetics (Closed 2011) (011005100)
- id
- 247a416a-6792-42ad-8f8d-57c4c47f4086 (old id 332290)
- date added to LUP
- 2016-04-01 15:20:32
- date last changed
- 2022-03-30 00:53:31
@article{247a416a-6792-42ad-8f8d-57c4c47f4086,
abstract = {{It has been suggested that the increase in the number of Hox genes may have been one of the key events in vertebrate evolution. Invertebrates have one Hox cluster, while mammals have four. Interestingly, the number of Hox gene clusters is greater in the teleost fishes, zebrafish and medaka, than in mouse and human. The greater number of Hox clusters in the teleosts suggests that Hox gene duplication events have occurred during the radiation of ray-finned fishes. The question is when the Hox gene duplication event(s) that lead to seven Hox clusters in the teleosts actually occurred. We have addressed this question by studying the Hox genes in the bichir, Polypterus palmas. A preliminary PCR-estimation of the number of Hox genes suggests that Polypterus has five different Hox9 cognate group genes, which may be an indication of more than four Hox clusters in the bichir.}},
author = {{Ledje, Christina and Kim, Chang-aeB and Ruddle, Francis H}},
issn = {{0022-104X}},
language = {{eng}},
number = {{2}},
pages = {{107--111}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Journal of Experimental Zoology}},
title = {{Characterization of Hox genes in the bichir, Polypterus palmas}},
url = {{http://dx.doi.org/10.1002/jez.10152}},
doi = {{10.1002/jez.10152}},
volume = {{294}},
year = {{2002}},
}