A case of Mycobacterium goodii prosthetic valve endocarditis in a non-immunocompromised patient: use of 16S rDNA analysis for rapid diagnosis
(2012) In BMC Infectious Diseases 12.- Abstract
- Background: Mycobacterium goodii is a rare cause of significant infection. M. goodii has mainly been associated with lymphadenitis, cellulitis, osteomyelitis, and wound infection. Case presentation: A case of a 76-year-old Caucasian female is presented. The patient developed a prosthetic valve endocarditis caused by M. goodii. She had also suffered from severe neurological symptoms related to a septic emboli that could be demonstrated as an ischemic lesion found on CT of the brain. Transesophageal echocardiography verified a large vegetation attached to the prosthetic valve. Commonly used blood culture bottles showed growth of the bacteria after 3 days. Conclusions: Although M. goodii is rarely involved in these kinds of severe infections,... (More)
- Background: Mycobacterium goodii is a rare cause of significant infection. M. goodii has mainly been associated with lymphadenitis, cellulitis, osteomyelitis, and wound infection. Case presentation: A case of a 76-year-old Caucasian female is presented. The patient developed a prosthetic valve endocarditis caused by M. goodii. She had also suffered from severe neurological symptoms related to a septic emboli that could be demonstrated as an ischemic lesion found on CT of the brain. Transesophageal echocardiography verified a large vegetation attached to the prosthetic valve. Commonly used blood culture bottles showed growth of the bacteria after 3 days. Conclusions: Although M. goodii is rarely involved in these kinds of severe infections, rapidly growing mycobacteria should be recognized during conventional bacterial investigations and identified by molecular tools such as analysis of 16S rDNA. Species identification of nontuberculous mycobacteria is demanding and is preferably done in collaboration with a mycobacterial laboratory. An early diagnosis provides the opportunity for adequate treatment. In the present case, prolonged antimicrobial treatment and surgery with replacement of the prosthetic valve was successful. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3683618
- author
- Jönsson, Göran LU ; Rydberg, Johan LU ; Sturegård, Erik LU and Christensson, Bertil LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Mycobacterium goodii, NTM, Endocarditis, Septic emboli, Prosthetic, valve, 16S rDNA analysis
- in
- BMC Infectious Diseases
- volume
- 12
- article number
- 301
- publisher
- BioMed Central (BMC)
- external identifiers
-
- wos:000315398700001
- scopus:84874000128
- pmid:23151090
- ISSN
- 1471-2334
- DOI
- 10.1186/1471-2334-12-301
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Microbiology, Immunology and Glycobiology - MIG (013025200), Division of Medical Microbiology (013250400), Division of Infection Medicine (SUS) (013008000), Clinical Microbiology, Malmö (013011000)
- id
- 32f50aeb-ec95-466e-bec7-4e99e0f38c96 (old id 3683618)
- date added to LUP
- 2016-04-01 14:20:51
- date last changed
- 2022-01-28 00:07:38
@article{32f50aeb-ec95-466e-bec7-4e99e0f38c96,
abstract = {{Background: Mycobacterium goodii is a rare cause of significant infection. M. goodii has mainly been associated with lymphadenitis, cellulitis, osteomyelitis, and wound infection. Case presentation: A case of a 76-year-old Caucasian female is presented. The patient developed a prosthetic valve endocarditis caused by M. goodii. She had also suffered from severe neurological symptoms related to a septic emboli that could be demonstrated as an ischemic lesion found on CT of the brain. Transesophageal echocardiography verified a large vegetation attached to the prosthetic valve. Commonly used blood culture bottles showed growth of the bacteria after 3 days. Conclusions: Although M. goodii is rarely involved in these kinds of severe infections, rapidly growing mycobacteria should be recognized during conventional bacterial investigations and identified by molecular tools such as analysis of 16S rDNA. Species identification of nontuberculous mycobacteria is demanding and is preferably done in collaboration with a mycobacterial laboratory. An early diagnosis provides the opportunity for adequate treatment. In the present case, prolonged antimicrobial treatment and surgery with replacement of the prosthetic valve was successful.}},
author = {{Jönsson, Göran and Rydberg, Johan and Sturegård, Erik and Christensson, Bertil}},
issn = {{1471-2334}},
keywords = {{Mycobacterium goodii; NTM; Endocarditis; Septic emboli; Prosthetic; valve; 16S rDNA analysis}},
language = {{eng}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Infectious Diseases}},
title = {{A case of Mycobacterium goodii prosthetic valve endocarditis in a non-immunocompromised patient: use of 16S rDNA analysis for rapid diagnosis}},
url = {{https://lup.lub.lu.se/search/files/3925456/4053678.pdf}},
doi = {{10.1186/1471-2334-12-301}},
volume = {{12}},
year = {{2012}},
}