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Changes in glycoprotein expression between primary breast tumour and synchronous lymph node metastases or asynchronous distant metastases.

Kurbasic, Emila LU ; Sjöström, Martin LU ; Krogh, Morten ; Folkesson, Elin LU ; Grabau, Dorthe LU ; Hansson, Karin M ; Rydén, Lisa LU orcid ; Waldemarson, Sofia LU ; James, Peter LU orcid and Niméus, Emma LU (2015) In Clinical Proteomics 12(1).
Abstract
Breast cancer is a very heterogeneous disease and some patients are cured by the surgical removal of the primary tumour whilst other patients suffer from metastasis and spreading of the disease, despite adjuvant therapy. A number of prognostic and treatment predictive factors have been identified such as tumour size, oestrogen (ER) and progesterone (PgR) receptor status, human epidermal growth factor receptor type 2 (HER2) status, histological grade, Ki67 and age. Lymph node involvement is also assessed during surgery to determine if the tumour has spread which requires dissection of the axilla and adjuvant treatment. The prognostic and treatment predictive factors assessing the nature of the tumour are all routinely based on the status of... (More)
Breast cancer is a very heterogeneous disease and some patients are cured by the surgical removal of the primary tumour whilst other patients suffer from metastasis and spreading of the disease, despite adjuvant therapy. A number of prognostic and treatment predictive factors have been identified such as tumour size, oestrogen (ER) and progesterone (PgR) receptor status, human epidermal growth factor receptor type 2 (HER2) status, histological grade, Ki67 and age. Lymph node involvement is also assessed during surgery to determine if the tumour has spread which requires dissection of the axilla and adjuvant treatment. The prognostic and treatment predictive factors assessing the nature of the tumour are all routinely based on the status of the primary tumour. (Less)
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author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Proteomics
volume
12
issue
1
article number
13
publisher
Humana Press
external identifiers
  • pmid:25991917
  • wos:000371208900001
  • pmid:25991917
  • scopus:84988734786
ISSN
1559-0275
DOI
10.1186/s12014-015-9084-7
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pathology, (Lund) (013030000), Oncology, MV (013035000), Surgery (Lund) (013009000), Connective Tissue Biology (013230151)
id
f494490e-1768-4a13-aee8-bde9bbd65b35 (old id 5448566)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25991917?dopt=Abstract
date added to LUP
2016-04-04 07:37:58
date last changed
2023-10-17 16:08:57
@article{f494490e-1768-4a13-aee8-bde9bbd65b35,
  abstract     = {{Breast cancer is a very heterogeneous disease and some patients are cured by the surgical removal of the primary tumour whilst other patients suffer from metastasis and spreading of the disease, despite adjuvant therapy. A number of prognostic and treatment predictive factors have been identified such as tumour size, oestrogen (ER) and progesterone (PgR) receptor status, human epidermal growth factor receptor type 2 (HER2) status, histological grade, Ki67 and age. Lymph node involvement is also assessed during surgery to determine if the tumour has spread which requires dissection of the axilla and adjuvant treatment. The prognostic and treatment predictive factors assessing the nature of the tumour are all routinely based on the status of the primary tumour.}},
  author       = {{Kurbasic, Emila and Sjöström, Martin and Krogh, Morten and Folkesson, Elin and Grabau, Dorthe and Hansson, Karin M and Rydén, Lisa and Waldemarson, Sofia and James, Peter and Niméus, Emma}},
  issn         = {{1559-0275}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Humana Press}},
  series       = {{Clinical Proteomics}},
  title        = {{Changes in glycoprotein expression between primary breast tumour and synchronous lymph node metastases or asynchronous distant metastases.}},
  url          = {{https://lup.lub.lu.se/search/files/5146109/8522257.pdf}},
  doi          = {{10.1186/s12014-015-9084-7}},
  volume       = {{12}},
  year         = {{2015}},
}