A follow-up study of Nordic multiple sclerosis candidate gene regions
(2007) In Multiple Sclerosis Journal 13(5). p.584-589- Abstract
- In this study, the results from three Nordic linkage disequilibrium screens in multiple sclerosis (MS) were investigated, in a new sample set of 314 Nordic MS trios from Denmark, Norway, Sweden and Iceland. Among 30 non-HLA and two HLA microsatellite markers individually genotyped, eight markers displayed distorted transmission with uncorrected P-value <0.05, ranked in this order: D6S2443 (6p21.32, HLA class II) (P corrected =0.01), D2S2201 (2p24), D19S552 (19q13), D3S3584 (3q21), D17S975 (17q11), DIS2627 (1p22), D6S273 (6p21.33, HLA class III) and D72S1051 (12q23). These non-HLA regions need further investigation as possible MS candidate gene regions in our population.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/648294
- author
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- sclerosis, Nordic countries, multiple, LID screens, HLA, genetics, candidate regions, GAMES
- in
- Multiple Sclerosis Journal
- volume
- 13
- issue
- 5
- pages
- 584 - 589
- publisher
- SAGE Publications
- external identifiers
-
- wos:000247376100003
- scopus:34047204808
- ISSN
- 1477-0970
- DOI
- 10.1177/1352458506071790
- language
- English
- LU publication?
- yes
- id
- 35077d30-32d3-4ca1-9621-41b97940a1a4 (old id 648294)
- date added to LUP
- 2016-04-01 12:13:41
- date last changed
- 2022-03-28 22:02:19
@article{35077d30-32d3-4ca1-9621-41b97940a1a4, abstract = {{In this study, the results from three Nordic linkage disequilibrium screens in multiple sclerosis (MS) were investigated, in a new sample set of 314 Nordic MS trios from Denmark, Norway, Sweden and Iceland. Among 30 non-HLA and two HLA microsatellite markers individually genotyped, eight markers displayed distorted transmission with uncorrected P-value <0.05, ranked in this order: D6S2443 (6p21.32, HLA class II) (P corrected =0.01), D2S2201 (2p24), D19S552 (19q13), D3S3584 (3q21), D17S975 (17q11), DIS2627 (1p22), D6S273 (6p21.33, HLA class III) and D72S1051 (12q23). These non-HLA regions need further investigation as possible MS candidate gene regions in our population.}}, author = {{Datta, P. and Harbo, H. F. and Ryder, L. P. and Akesson, E. and Benedikz, J. and Celius, E. G. and Andersen, O. and Myhe, K-M and Sandberg Wollheim, Magnhild and Hillert, J. and Svejgaard, A. and Sorensen, P. S. and Spurkland, A. and Oturai, A.}}, issn = {{1477-0970}}, keywords = {{sclerosis; Nordic countries; multiple; LID screens; HLA; genetics; candidate regions; GAMES}}, language = {{eng}}, number = {{5}}, pages = {{584--589}}, publisher = {{SAGE Publications}}, series = {{Multiple Sclerosis Journal}}, title = {{A follow-up study of Nordic multiple sclerosis candidate gene regions}}, url = {{http://dx.doi.org/10.1177/1352458506071790}}, doi = {{10.1177/1352458506071790}}, volume = {{13}}, year = {{2007}}, }