The number and characteristics of prevalent vertebral fractures in elderly men are associated with low bone mass and osteoporosis.
(2015) In The Bone & Joint Journal 97B(8). p.1106-1110- Abstract
- We sought to determine whether specific characteristics of vertebral fractures in elderly men are associated with low bone mineral density (BMD) and osteoporosis. Mister osteoporosis Sweden is a population based cohort study involving 3014 men aged 69 to 81 years. Of these, 1427 had readable lateral radiographs of the thoracic and lumbar spine. Total body (TB) BMD (g/cm²) and total right hip (TH) BMD were measured by dual energy x-ray absorptiometry. The proportion of men with osteoporosis was calculated from TH BMD. There were 215 men (15.1%) with a vertebral fracture. Those with a fracture had lower TB BMD than those without (p < 0.001). Among men with a fracture, TB BMD was lower in those with more than three fractures (p = 0.02),... (More)
- We sought to determine whether specific characteristics of vertebral fractures in elderly men are associated with low bone mineral density (BMD) and osteoporosis. Mister osteoporosis Sweden is a population based cohort study involving 3014 men aged 69 to 81 years. Of these, 1427 had readable lateral radiographs of the thoracic and lumbar spine. Total body (TB) BMD (g/cm²) and total right hip (TH) BMD were measured by dual energy x-ray absorptiometry. The proportion of men with osteoporosis was calculated from TH BMD. There were 215 men (15.1%) with a vertebral fracture. Those with a fracture had lower TB BMD than those without (p < 0.001). Among men with a fracture, TB BMD was lower in those with more than three fractures (p = 0.02), those with biconcave fractures (p = 0.02) and those with vertebral body compression of > 42% (worst quartile) (p = 0.03). The mean odds ratio (OR) for having osteoporosis when having any type of vertebral fracture was 6.1 (95% confidence interval (CI) 3.9 to 9.5) compared with those without a fracture. A combination of more than three fractures and compression in the worst quartile had a mean OR of 114.2 (95% CI 6.7 to 1938.3) of having osteoporosis compared with those without a fracture. We recommend BMD studies to be undertaken in these subcohorts of elderly men with a vertebral fracture. Cite this article: 2015;97-B:1106-10. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7850906
- author
- Kherad, Mehrsa LU ; Mellström, D ; Rosengren, Björn LU ; Hasserius, Ralph LU ; Nilsson, Jan-Åke LU ; Redlund-Johnell, Inga LU ; Ohlsson, C ; Lorentzon, M and Karlsson, Magnus K LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- The Bone & Joint Journal
- volume
- 97B
- issue
- 8
- pages
- 1106 - 1110
- publisher
- British Editorial Society of Bone & Joint Surgery
- external identifiers
-
- pmid:26224829
- wos:000359093100017
- scopus:84938364335
- pmid:26224829
- ISSN
- 2049-4408
- DOI
- 10.1302/0301-620X.97B8.35032
- language
- English
- LU publication?
- yes
- id
- c71128f0-896f-4842-a939-26c1950523e1 (old id 7850906)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26224829?dopt=Abstract
- date added to LUP
- 2016-04-01 11:03:28
- date last changed
- 2022-03-12 19:30:54
@article{c71128f0-896f-4842-a939-26c1950523e1,
abstract = {{We sought to determine whether specific characteristics of vertebral fractures in elderly men are associated with low bone mineral density (BMD) and osteoporosis. Mister osteoporosis Sweden is a population based cohort study involving 3014 men aged 69 to 81 years. Of these, 1427 had readable lateral radiographs of the thoracic and lumbar spine. Total body (TB) BMD (g/cm²) and total right hip (TH) BMD were measured by dual energy x-ray absorptiometry. The proportion of men with osteoporosis was calculated from TH BMD. There were 215 men (15.1%) with a vertebral fracture. Those with a fracture had lower TB BMD than those without (p < 0.001). Among men with a fracture, TB BMD was lower in those with more than three fractures (p = 0.02), those with biconcave fractures (p = 0.02) and those with vertebral body compression of > 42% (worst quartile) (p = 0.03). The mean odds ratio (OR) for having osteoporosis when having any type of vertebral fracture was 6.1 (95% confidence interval (CI) 3.9 to 9.5) compared with those without a fracture. A combination of more than three fractures and compression in the worst quartile had a mean OR of 114.2 (95% CI 6.7 to 1938.3) of having osteoporosis compared with those without a fracture. We recommend BMD studies to be undertaken in these subcohorts of elderly men with a vertebral fracture. Cite this article: 2015;97-B:1106-10.}},
author = {{Kherad, Mehrsa and Mellström, D and Rosengren, Björn and Hasserius, Ralph and Nilsson, Jan-Åke and Redlund-Johnell, Inga and Ohlsson, C and Lorentzon, M and Karlsson, Magnus K}},
issn = {{2049-4408}},
language = {{eng}},
number = {{8}},
pages = {{1106--1110}},
publisher = {{British Editorial Society of Bone & Joint Surgery}},
series = {{The Bone & Joint Journal}},
title = {{The number and characteristics of prevalent vertebral fractures in elderly men are associated with low bone mass and osteoporosis.}},
url = {{http://dx.doi.org/10.1302/0301-620X.97B8.35032}},
doi = {{10.1302/0301-620X.97B8.35032}},
volume = {{97B}},
year = {{2015}},
}