Optogenetic control of human neurons in organotypic brain cultures
Andersson, My LU
; Avaliani, Natalia
; Svensson, Andreas
LU
; Wickham, Jenny
LU
; Pinborg, Lars H.
; Jespersen, Bo
; Christiansen, Søren H.
; Bengzon, Johan
LU
; Woldbye, David P D
and Kokaia, Merab
LU
(2016)
In Scientific Reports
6.
- Abstract
Optogenetics is one of the most powerful tools in neuroscience, allowing for selective control of specific neuronal populations in the brain of experimental animals, including mammals. We report, for the first time, the application of optogenetic tools to human brain tissue providing a proof-of-concept for the use of optogenetics in neuromodulation of human cortical and hippocampal neurons as a possible tool to explore network mechanisms and develop future therapeutic strategies.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8edb0254-31c2-4c63-8741-718da3cfe8f9
- author
- Andersson, My
LU
; Avaliani, Natalia
; Svensson, Andreas
LU
; Wickham, Jenny
LU
; Pinborg, Lars H.
; Jespersen, Bo
; Christiansen, Søren H.
; Bengzon, Johan
LU
; Woldbye, David P D
and Kokaia, Merab
LU
- organization
- publishing date
- 2016-04-21
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scientific Reports
- volume
- 6
- article number
- 24818
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:27098488
- wos:000374502000001
- scopus:84964617583
- ISSN
- 2045-2322
- DOI
- 10.1038/srep24818
- language
- English
- LU publication?
- yes
- id
- 8edb0254-31c2-4c63-8741-718da3cfe8f9
- date added to LUP
- 2016-09-30 13:40:34
- date last changed
- 2024-04-19 09:41:58
@article{8edb0254-31c2-4c63-8741-718da3cfe8f9,
abstract = {{<p>Optogenetics is one of the most powerful tools in neuroscience, allowing for selective control of specific neuronal populations in the brain of experimental animals, including mammals. We report, for the first time, the application of optogenetic tools to human brain tissue providing a proof-of-concept for the use of optogenetics in neuromodulation of human cortical and hippocampal neurons as a possible tool to explore network mechanisms and develop future therapeutic strategies.</p>}},
author = {{Andersson, My and Avaliani, Natalia and Svensson, Andreas and Wickham, Jenny and Pinborg, Lars H. and Jespersen, Bo and Christiansen, Søren H. and Bengzon, Johan and Woldbye, David P D and Kokaia, Merab}},
issn = {{2045-2322}},
language = {{eng}},
month = {{04}},
publisher = {{Nature Publishing Group}},
series = {{Scientific Reports}},
title = {{Optogenetic control of human neurons in organotypic brain cultures}},
url = {{http://dx.doi.org/10.1038/srep24818}},
doi = {{10.1038/srep24818}},
volume = {{6}},
year = {{2016}},
}