C-band heteromorphism in breast cancer patients
Berger, Roland ; Bernheim, Alain ; Kristoffersson, Ulf LU ; Mitelman, Felix LU
and Olsson, Håkan
LU
(1985)
In Cancer Genetics and Cytogenetics
18(1).
p.37-42
- Abstract
The pattern of heteromorphism in the C-band-positive constitutive heterochromatin of human chromosomes #1, #9, and #16 was studied in peripheral lymphocytes of 54 breast cancer patients and 78 control individuals. The parameters of the heterochromatic regions analyzed were relative size, symmetry-asymmetry within homologous pairs, and prevalence of inversions. Significant differences between the two groups were found in C-band size of chromosomes #1, #9, and #16 and in incidence of inversions on chromosomes #1 and #9. Significant differences were noted between premenopausal and postmenopausal cancer patients in regard to inversions on chromosome #9 and between familial and sporadic patients in regard to C-band size on chromosome #16.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/01d90705-95ff-455b-98cb-de8348f68032
- author
- Berger, Roland
; Bernheim, Alain
; Kristoffersson, Ulf
LU
; Mitelman, Felix
LU
and Olsson, Håkan
LU
- organization
- publishing date
- 1985-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cancer Genetics and Cytogenetics
- volume
- 18
- issue
- 1
- pages
- 6 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:0022257061
- pmid:4027949
- ISSN
- 0165-4608
- DOI
- 10.1016/0165-4608(85)90037-8
- language
- English
- LU publication?
- yes
- id
- 01d90705-95ff-455b-98cb-de8348f68032
- date added to LUP
- 2018-12-12 08:48:24
- date last changed
- 2024-04-01 16:01:56
@article{01d90705-95ff-455b-98cb-de8348f68032,
abstract = {{<p>The pattern of heteromorphism in the C-band-positive constitutive heterochromatin of human chromosomes #1, #9, and #16 was studied in peripheral lymphocytes of 54 breast cancer patients and 78 control individuals. The parameters of the heterochromatic regions analyzed were relative size, symmetry-asymmetry within homologous pairs, and prevalence of inversions. Significant differences between the two groups were found in C-band size of chromosomes #1, #9, and #16 and in incidence of inversions on chromosomes #1 and #9. Significant differences were noted between premenopausal and postmenopausal cancer patients in regard to inversions on chromosome #9 and between familial and sporadic patients in regard to C-band size on chromosome #16.</p>}},
author = {{Berger, Roland and Bernheim, Alain and Kristoffersson, Ulf and Mitelman, Felix and Olsson, Håkan}},
issn = {{0165-4608}},
language = {{eng}},
month = {{01}},
number = {{1}},
pages = {{37--42}},
publisher = {{Elsevier}},
series = {{Cancer Genetics and Cytogenetics}},
title = {{C-band heteromorphism in breast cancer patients}},
url = {{http://dx.doi.org/10.1016/0165-4608(85)90037-8}},
doi = {{10.1016/0165-4608(85)90037-8}},
volume = {{18}},
year = {{1985}},
}