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Evaluation of circulating immune complex-like material for development of skin reactions in connection with penicillin therapy

Ahlstedt, S ; Bjursten, Lars Magnus LU ; Hanson, L A ; Lidin-Janson, G ; Mobacken, H and Belin, L (1981) In International Archives of Allergy and Applied Immunology 64(2). p.195-200
Abstract
The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions... (More)
The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions often seen in connection with penicillin treatment. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Archives of Allergy and Applied Immunology
volume
64
issue
2
pages
195 - 200
publisher
Karger
external identifiers
  • pmid:7461855
  • scopus:0019428194
ISSN
0020-5915
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Bioimplant Research (013242910)
id
26c80c54-0d2f-451c-beb1-80d35580f997 (old id 1102801)
date added to LUP
2016-04-01 16:27:10
date last changed
2021-01-03 04:51:04
@article{26c80c54-0d2f-451c-beb1-80d35580f997,
  abstract     = {{The levels of immune complex-like material in serum from 18 patients in connection with skin eruptions appearing during penicillin therapy were determined with a modified ELISA. Immune complex-like material could only be shown in the serum of 3 out of the 17 patients. However, according to ELISA results, the complexes appeared without the simultaneous presence of penicilloyl-specific antibodies. Neither could penicilloyl-specific antibodies be recorded in 9 patient treated with parenteral penicillin without adverse reactions. 3 of these patients had immune complex-like material in their serum. It was concluded that immune complex-like material with penicilloyl specificity is not likely to contribute to the development of skin eruptions often seen in connection with penicillin treatment.}},
  author       = {{Ahlstedt, S and Bjursten, Lars Magnus and Hanson, L A and Lidin-Janson, G and Mobacken, H and Belin, L}},
  issn         = {{0020-5915}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{195--200}},
  publisher    = {{Karger}},
  series       = {{International Archives of Allergy and Applied Immunology}},
  title        = {{Evaluation of circulating immune complex-like material for development of skin reactions in connection with penicillin therapy}},
  volume       = {{64}},
  year         = {{1981}},
}