Circadian variation in human cerebrospinal fluid production measured by magnetic resonance imaging
(1992) In American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 262(1). p.20-24- Abstract
- Recent advances in magnetic resonance imaging have made it possible to visualize and quantify flow of cerebrospinal fluid (CSF) in the brain. The net flow of CSF through the cerebral aqueduct was used to measure CSF production in six normal volunteers at different times during a 24-h period. CSF production varied greatly both intra- and interindividually. The average CSF production in each time interval showed a clear tendency to circadian variation, with a minimum production 30% of maximum values (12 +/- 7 ml/h) approximately 1800 h and a nightly peak production approximately 0200 h of 42 +/- 2 ml/h. The total CSF production during the whole 24-h period, calculated as an average of all measurements, was 650 ml for the whole group and 630... (More)
- Recent advances in magnetic resonance imaging have made it possible to visualize and quantify flow of cerebrospinal fluid (CSF) in the brain. The net flow of CSF through the cerebral aqueduct was used to measure CSF production in six normal volunteers at different times during a 24-h period. CSF production varied greatly both intra- and interindividually. The average CSF production in each time interval showed a clear tendency to circadian variation, with a minimum production 30% of maximum values (12 +/- 7 ml/h) approximately 1800 h and a nightly peak production approximately 0200 h of 42 +/- 2 ml/h. The total CSF production during the whole 24-h period, calculated as an average of all measurements, was 650 ml for the whole group and 630 ml for repeated measurements in each time interval in one of the volunteers. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1106435
- author
- Nilsson, C ; Ståhlberg, Freddy LU ; Thomsen, C ; Henriksen, O ; Herning, M and Owman, Christer LU
- organization
- publishing date
- 1992
- type
- Contribution to journal
- publication status
- published
- subject
- in
- American Journal of Physiology: Regulatory, Integrative and Comparative Physiology
- volume
- 262
- issue
- 1
- pages
- 20 - 24
- publisher
- American Physiological Society
- external identifiers
-
- pmid:1733335
- scopus:0026583226
- ISSN
- 1522-1490
- DOI
- 10.1152/ajpregu.1992.262.1.R20
- language
- English
- LU publication?
- yes
- id
- af390186-351e-41c7-87b1-de6c38d22634 (old id 1106435)
- date added to LUP
- 2016-04-01 17:00:27
- date last changed
- 2021-09-26 03:03:43
@article{af390186-351e-41c7-87b1-de6c38d22634,
abstract = {{Recent advances in magnetic resonance imaging have made it possible to visualize and quantify flow of cerebrospinal fluid (CSF) in the brain. The net flow of CSF through the cerebral aqueduct was used to measure CSF production in six normal volunteers at different times during a 24-h period. CSF production varied greatly both intra- and interindividually. The average CSF production in each time interval showed a clear tendency to circadian variation, with a minimum production 30% of maximum values (12 +/- 7 ml/h) approximately 1800 h and a nightly peak production approximately 0200 h of 42 +/- 2 ml/h. The total CSF production during the whole 24-h period, calculated as an average of all measurements, was 650 ml for the whole group and 630 ml for repeated measurements in each time interval in one of the volunteers.}},
author = {{Nilsson, C and Ståhlberg, Freddy and Thomsen, C and Henriksen, O and Herning, M and Owman, Christer}},
issn = {{1522-1490}},
language = {{eng}},
number = {{1}},
pages = {{20--24}},
publisher = {{American Physiological Society}},
series = {{American Journal of Physiology: Regulatory, Integrative and Comparative Physiology}},
title = {{Circadian variation in human cerebrospinal fluid production measured by magnetic resonance imaging}},
url = {{http://dx.doi.org/10.1152/ajpregu.1992.262.1.R20}},
doi = {{10.1152/ajpregu.1992.262.1.R20}},
volume = {{262}},
year = {{1992}},
}