Long-term effects on cholesterol levels and the utilization of lipid-lowering drugs of a hospital based programme for seconadry prevention of coronary artery disease
(2001) In European Journal of Cardiovascular Prevention & Rehabilitation 8(4). p.243-248- Abstract
- Background: The study was designed to determine whether a 1-year hospital-based secondary prevention programme would have any long-term effects on serum lipid levels and the use of lipid-lowering drugs in patients with coronary artery disease 4 years after referral to primary care facilities for follow-up.
Design/methods: After acute myocardial infarction or coronary bypass surgery, 241 consecutive patients were randomly assigned to conventional care (CC) by the primary health care facilities or to a 1-year hospital-based secondary prevention programme (SPP) with target levels for serum cholesterol (<5.2 mmol/l) and triglycerides (<1.5 mmol/l). After 1 year all patients were referred to the primary care sector for... (More) - Background: The study was designed to determine whether a 1-year hospital-based secondary prevention programme would have any long-term effects on serum lipid levels and the use of lipid-lowering drugs in patients with coronary artery disease 4 years after referral to primary care facilities for follow-up.
Design/methods: After acute myocardial infarction or coronary bypass surgery, 241 consecutive patients were randomly assigned to conventional care (CC) by the primary health care facilities or to a 1-year hospital-based secondary prevention programme (SPP) with target levels for serum cholesterol (<5.2 mmol/l) and triglycerides (<1.5 mmol/l). After 1 year all patients were referred to the primary care sector for a further 4-year follow-up.
Results: At the 1-year follow-up there was a significant decrease in serum cholesterol, LDL-cholesterol and triglyceride levels in the SPP group but no change in the CC group, and lipid-lowering drugs were used more frequently in the SPP group. These changes were maintained after 5 years. The proportion of patients achieving target serum cholesterol and triglyceride levels were larger in the SPP group.
Conclusions: Initiatives regarding cholesterol lowering and drug treatment taken by specialists within a structured hospital-based SPP have long-term impact. Accordingly, drug treatment should be initiated and adjusted to adequate doses before patients are referred to primary care for follow-up. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1121437
- author
- Stagmo, Martin LU ; Westin, L ; Carlsson, R and Israelsson, B
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Journal of Cardiovascular Prevention & Rehabilitation
- volume
- 8
- issue
- 4
- pages
- 243 - 248
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- scopus:84992854114
- ISSN
- 1741-8275
- language
- English
- LU publication?
- yes
- id
- b574ac35-7dfc-4c62-a8dc-5fe34616a588 (old id 1121437)
- date added to LUP
- 2016-04-01 12:13:47
- date last changed
- 2022-01-27 00:44:09
@article{b574ac35-7dfc-4c62-a8dc-5fe34616a588, abstract = {{Background: The study was designed to determine whether a 1-year hospital-based secondary prevention programme would have any long-term effects on serum lipid levels and the use of lipid-lowering drugs in patients with coronary artery disease 4 years after referral to primary care facilities for follow-up.<br/><br> <br/><br> Design/methods: After acute myocardial infarction or coronary bypass surgery, 241 consecutive patients were randomly assigned to conventional care (CC) by the primary health care facilities or to a 1-year hospital-based secondary prevention programme (SPP) with target levels for serum cholesterol (<5.2 mmol/l) and triglycerides (<1.5 mmol/l). After 1 year all patients were referred to the primary care sector for a further 4-year follow-up.<br/><br> <br/><br> Results: At the 1-year follow-up there was a significant decrease in serum cholesterol, LDL-cholesterol and triglyceride levels in the SPP group but no change in the CC group, and lipid-lowering drugs were used more frequently in the SPP group. These changes were maintained after 5 years. The proportion of patients achieving target serum cholesterol and triglyceride levels were larger in the SPP group.<br/><br> <br/><br> Conclusions: Initiatives regarding cholesterol lowering and drug treatment taken by specialists within a structured hospital-based SPP have long-term impact. Accordingly, drug treatment should be initiated and adjusted to adequate doses before patients are referred to primary care for follow-up.}}, author = {{Stagmo, Martin and Westin, L and Carlsson, R and Israelsson, B}}, issn = {{1741-8275}}, language = {{eng}}, number = {{4}}, pages = {{243--248}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{European Journal of Cardiovascular Prevention & Rehabilitation}}, title = {{Long-term effects on cholesterol levels and the utilization of lipid-lowering drugs of a hospital based programme for seconadry prevention of coronary artery disease}}, volume = {{8}}, year = {{2001}}, }