Clinical manifestations and coronary artery disease risk factors at diagnosis of systemic lupus erythematosus: data from an international inception cohort
(2007) In Lupus 16(9). p.731-735- Abstract
- Systemic Lupus International Collaborating Clinics (SLICC) comprises 27 centres from 11 countries. An inception cohort of 918 SLE patients has been assembled according to a standardized protocol between 2000 and 2006. Clinical features, classic coronary artery disease (CAD) risk factors, as well as other potential risk factors were collected. Of the 918 patients 89% were females, and of multi racial origin. Less than half the patients were living in a permanent relationship, 58% had post secondary education and 51% were employed. Eight percent had family history of SLE. At enrolment, with at mean age of diagnosis of 34.5 years, a significant number of patients already had CAD risk factors, such as hypertension (33%) and... (More)
- Systemic Lupus International Collaborating Clinics (SLICC) comprises 27 centres from 11 countries. An inception cohort of 918 SLE patients has been assembled according to a standardized protocol between 2000 and 2006. Clinical features, classic coronary artery disease (CAD) risk factors, as well as other potential risk factors were collected. Of the 918 patients 89% were females, and of multi racial origin. Less than half the patients were living in a permanent relationship, 58% had post secondary education and 51% were employed. Eight percent had family history of SLE. At enrolment, with at mean age of diagnosis of 34.5 years, a significant number of patients already had CAD risk factors, such as hypertension (33%) and hypercholesterolemia (36%). Only 15% of the patients were postmenopausal, 16% were current smokers and 3.6% had diabetes at entry to the SLICC-RAS (Registry for Atherosclerosis). A number of patients in this multi-racial, multi-ethnic inception cohort of lupus patients have classic CAD risk factors within a mean of 5.4 months from diagnosis. This cohort will be increased to 1500 patients to be followed yearly for 10 years. This will provide a unique opportunity to evaluate risk factors for accelerated atherosclerosis in SLE. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1142696
- author
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Lupus
- volume
- 16
- issue
- 9
- pages
- 731 - 735
- publisher
- SAGE Publications
- external identifiers
-
- pmid:17728367
- scopus:34948827357
- ISSN
- 0961-2033
- DOI
- 10.1177/0961203307081113
- language
- English
- LU publication?
- yes
- id
- 6f53fca0-55e9-4808-b229-cfbe4f6bf436 (old id 1142696)
- date added to LUP
- 2016-04-01 12:08:31
- date last changed
- 2022-04-29 01:12:30
@article{6f53fca0-55e9-4808-b229-cfbe4f6bf436, abstract = {{Systemic Lupus International Collaborating Clinics (SLICC) comprises 27 centres from 11 countries. An inception cohort of 918 SLE patients has been assembled according to a standardized protocol between 2000 and 2006. Clinical features, classic coronary artery disease (CAD) risk factors, as well as other potential risk factors were collected. Of the 918 patients 89% were females, and of multi racial origin. Less than half the patients were living in a permanent relationship, 58% had post secondary education and 51% were employed. Eight percent had family history of SLE. At enrolment, with at mean age of diagnosis of 34.5 years, a significant number of patients already had CAD risk factors, such as hypertension (33%) and hypercholesterolemia (36%). Only 15% of the patients were postmenopausal, 16% were current smokers and 3.6% had diabetes at entry to the SLICC-RAS (Registry for Atherosclerosis). A number of patients in this multi-racial, multi-ethnic inception cohort of lupus patients have classic CAD risk factors within a mean of 5.4 months from diagnosis. This cohort will be increased to 1500 patients to be followed yearly for 10 years. This will provide a unique opportunity to evaluate risk factors for accelerated atherosclerosis in SLE.}}, author = {{Urowitz, M B and Gladman, D and Ibanez, D and Fortin, P and Sanchez-Guerrero, J and Bae, S and Clarke, A and Bernatsky, S and Gordon, C and Hanly, J and Wallace, D and Isenberg, D and Ginzler, E and Merrill, J and Alarcon, G and Steinsson, K and Petri, M and Dooley, M A and Bruce, I and Manzi, S and Khamashta, M and Ramsey-Goldman, R and Zoma, A and Sturfelt, Gunnar and Nived, Ola and Maddison, P and Font, J and van Vollenhoven, R and Aranow, C and Kalunian, K and Stoll, T and Buyon, J}}, issn = {{0961-2033}}, language = {{eng}}, number = {{9}}, pages = {{731--735}}, publisher = {{SAGE Publications}}, series = {{Lupus}}, title = {{Clinical manifestations and coronary artery disease risk factors at diagnosis of systemic lupus erythematosus: data from an international inception cohort}}, url = {{http://dx.doi.org/10.1177/0961203307081113}}, doi = {{10.1177/0961203307081113}}, volume = {{16}}, year = {{2007}}, }