Cortical blood flow during head-up postural change in subjects with orthostatic hypotension
(1993) In Clinical autonomic research : official journal of the Clinical Autonomic Research Society 3(5). p.311-318- Abstract
- Regional cerebral blood flow was measured with the 133-Xenon inhalation method in seven healthy subjects with orthostatic hypotension not due to autonomic failure (i.e. non-neurogenic clinical disorder). Measurements were performed during supine rest and during head-up tilt (70 degrees). All subjects had a consistent drop in systolic blood pressure and the typical symptomatology of orthostatic hypotension. The results showed lower mean hemispheric blood flow during head-up tilt than during supine rest. In addition, a consistent and significant redistribution of the regional flow values was seen, with a reduction in frontal and an increase in postcentral areas. The frontal flow decrease during tilt was more marked than in subjects without... (More)
- Regional cerebral blood flow was measured with the 133-Xenon inhalation method in seven healthy subjects with orthostatic hypotension not due to autonomic failure (i.e. non-neurogenic clinical disorder). Measurements were performed during supine rest and during head-up tilt (70 degrees). All subjects had a consistent drop in systolic blood pressure and the typical symptomatology of orthostatic hypotension. The results showed lower mean hemispheric blood flow during head-up tilt than during supine rest. In addition, a consistent and significant redistribution of the regional flow values was seen, with a reduction in frontal and an increase in postcentral areas. The frontal flow decrease during tilt was more marked than in subjects without orthostatic hypotension and was not related to variations in the level of PCO2 or to respiration. In contrast to the clinical symptoms of orthostatic hypotension (dizziness, nausea, visual disturbances, and in some cases syncope), the cortical blood flow reduction was, however, relatively moderate. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1296276
- author
- Passant, Ulla LU ; Warkentin, Siegbert LU ; Minthon, Lennart LU ; Fäldt, Roger LU and Edvinsson, Lars LU
- organization
- publishing date
- 1993
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical autonomic research : official journal of the Clinical Autonomic Research Society
- volume
- 3
- issue
- 5
- pages
- 311 - 318
- publisher
- Springer
- external identifiers
-
- scopus:0027882566
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Faculty of Medicine (000022000), Department of Child and Youth Psychiatry (013303003), Department of Psychogeriatrics (013304000), Medicine (Lund) (013230025), Clinical Memory Research Unit (013242610)
- id
- d2400899-68dd-4cb9-8a7e-e2ecc894d8c2 (old id 1296276)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/8124063
- date added to LUP
- 2016-04-04 13:38:19
- date last changed
- 2024-01-13 08:36:23
@article{d2400899-68dd-4cb9-8a7e-e2ecc894d8c2,
abstract = {{Regional cerebral blood flow was measured with the 133-Xenon inhalation method in seven healthy subjects with orthostatic hypotension not due to autonomic failure (i.e. non-neurogenic clinical disorder). Measurements were performed during supine rest and during head-up tilt (70 degrees). All subjects had a consistent drop in systolic blood pressure and the typical symptomatology of orthostatic hypotension. The results showed lower mean hemispheric blood flow during head-up tilt than during supine rest. In addition, a consistent and significant redistribution of the regional flow values was seen, with a reduction in frontal and an increase in postcentral areas. The frontal flow decrease during tilt was more marked than in subjects without orthostatic hypotension and was not related to variations in the level of PCO2 or to respiration. In contrast to the clinical symptoms of orthostatic hypotension (dizziness, nausea, visual disturbances, and in some cases syncope), the cortical blood flow reduction was, however, relatively moderate.}},
author = {{Passant, Ulla and Warkentin, Siegbert and Minthon, Lennart and Fäldt, Roger and Edvinsson, Lars}},
language = {{eng}},
number = {{5}},
pages = {{311--318}},
publisher = {{Springer}},
series = {{Clinical autonomic research : official journal of the Clinical Autonomic Research Society}},
title = {{Cortical blood flow during head-up postural change in subjects with orthostatic hypotension}},
url = {{http://www.ncbi.nlm.nih.gov/pubmed/8124063}},
volume = {{3}},
year = {{1993}},
}