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Biocatalysts for selective introduction of oxygen

Leak, David J. ; Sheldon, Roger A. ; Woodley, John M. and Adlercreutz, Patrick LU orcid (2009) In Biocatalysis and Biotransformation 27(1). p.1-26
Abstract
Three types of oxygenase biocatalysts are treated in detail in this review: the non-haem iron alkene mono-oxygenases, the haem and vanadium haloperoxidases, and flavin-based Baeyer-Villiger mono-oxygenases. Other oxygenases are briefly included for comparison. Characteristics of the biocatalysts are presented, and the scope and limitations concerning their applicability for the selective introduction of oxygen are discussed. Key issues include catalytic activity, productivity, cloning and expression, as well as process engineering aspects. Various bottlenecks are identified for the different biocatalysts and measures to increase the number of oxygenase reactions in practical use are discussed.
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
chloroperoxidase, Mono-oxygenase, peroxidase, oxygenation
in
Biocatalysis and Biotransformation
volume
27
issue
1
pages
1 - 26
publisher
Taylor & Francis
external identifiers
  • wos:000261874600001
  • scopus:58049219004
ISSN
1024-2422
DOI
10.1080/10242420802393519
language
English
LU publication?
yes
id
a562cb3b-89da-4c9f-9488-15a38347a460 (old id 1313695)
date added to LUP
2016-04-01 12:21:02
date last changed
2022-01-27 02:29:27
@article{a562cb3b-89da-4c9f-9488-15a38347a460,
  abstract     = {{Three types of oxygenase biocatalysts are treated in detail in this review: the non-haem iron alkene mono-oxygenases, the haem and vanadium haloperoxidases, and flavin-based Baeyer-Villiger mono-oxygenases. Other oxygenases are briefly included for comparison. Characteristics of the biocatalysts are presented, and the scope and limitations concerning their applicability for the selective introduction of oxygen are discussed. Key issues include catalytic activity, productivity, cloning and expression, as well as process engineering aspects. Various bottlenecks are identified for the different biocatalysts and measures to increase the number of oxygenase reactions in practical use are discussed.}},
  author       = {{Leak, David J. and Sheldon, Roger A. and Woodley, John M. and Adlercreutz, Patrick}},
  issn         = {{1024-2422}},
  keywords     = {{chloroperoxidase; Mono-oxygenase; peroxidase; oxygenation}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{1--26}},
  publisher    = {{Taylor & Francis}},
  series       = {{Biocatalysis and Biotransformation}},
  title        = {{Biocatalysts for selective introduction of oxygen}},
  url          = {{http://dx.doi.org/10.1080/10242420802393519}},
  doi          = {{10.1080/10242420802393519}},
  volume       = {{27}},
  year         = {{2009}},
}