Polyneuritis cranialis presenting with anti-GQ1b IgG antibody.
(2009) In Journal of the Neurological Sciences 281. p.125-126- Abstract
- A 52-year-old man developed diplopia, a nasal voice, dysphagia, hoarseness and slight bilateral facial palsies. There was no ataxia, areflexia, limb weakness or sensory involvement. Serum anti-GQ1b IgG antibody was present. Treatment with intravenous immunoglobulin started, and the patient responded with a rapid resolution of symptoms. The diagnosis is consistent with polyneuritis cranialis which is considered to be a Guillain-Barre syndrome variant, a forme fruste, but very rare. The diagnosis can be difficult and a thorough investigation is required. Electrophysiological examination, laboratory evaluations, imaging and cerebrospinal fluid examination are often required in the investigations. Cranial neuropathy can be the presentation of... (More)
- A 52-year-old man developed diplopia, a nasal voice, dysphagia, hoarseness and slight bilateral facial palsies. There was no ataxia, areflexia, limb weakness or sensory involvement. Serum anti-GQ1b IgG antibody was present. Treatment with intravenous immunoglobulin started, and the patient responded with a rapid resolution of symptoms. The diagnosis is consistent with polyneuritis cranialis which is considered to be a Guillain-Barre syndrome variant, a forme fruste, but very rare. The diagnosis can be difficult and a thorough investigation is required. Electrophysiological examination, laboratory evaluations, imaging and cerebrospinal fluid examination are often required in the investigations. Cranial neuropathy can be the presentation of many disorders. Determination of anti-ganglioside antibodies as anti-GQ1b is valuable to the diagnosis, and shows the association with the Guillain-Barre syndrome. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1367452
- author
- Edvardsson, Bengt LU and Persson, Staffan LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the Neurological Sciences
- volume
- 281
- pages
- 125 - 126
- publisher
- Elsevier
- external identifiers
-
- wos:000266736800029
- pmid:19324375
- scopus:67349206126
- pmid:19324375
- ISSN
- 1878-5883
- DOI
- 10.1016/j.jns.2009.02.340
- language
- English
- LU publication?
- yes
- id
- 9a3fcc76-7ff7-4e06-9659-b11bead8e138 (old id 1367452)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19324375?dopt=Abstract
- date added to LUP
- 2016-04-04 07:03:10
- date last changed
- 2022-01-29 01:38:45
@article{9a3fcc76-7ff7-4e06-9659-b11bead8e138,
abstract = {{A 52-year-old man developed diplopia, a nasal voice, dysphagia, hoarseness and slight bilateral facial palsies. There was no ataxia, areflexia, limb weakness or sensory involvement. Serum anti-GQ1b IgG antibody was present. Treatment with intravenous immunoglobulin started, and the patient responded with a rapid resolution of symptoms. The diagnosis is consistent with polyneuritis cranialis which is considered to be a Guillain-Barre syndrome variant, a forme fruste, but very rare. The diagnosis can be difficult and a thorough investigation is required. Electrophysiological examination, laboratory evaluations, imaging and cerebrospinal fluid examination are often required in the investigations. Cranial neuropathy can be the presentation of many disorders. Determination of anti-ganglioside antibodies as anti-GQ1b is valuable to the diagnosis, and shows the association with the Guillain-Barre syndrome.}},
author = {{Edvardsson, Bengt and Persson, Staffan}},
issn = {{1878-5883}},
language = {{eng}},
pages = {{125--126}},
publisher = {{Elsevier}},
series = {{Journal of the Neurological Sciences}},
title = {{Polyneuritis cranialis presenting with anti-GQ1b IgG antibody.}},
url = {{http://dx.doi.org/10.1016/j.jns.2009.02.340}},
doi = {{10.1016/j.jns.2009.02.340}},
volume = {{281}},
year = {{2009}},
}