Classification of systemic sclerosis. Visions and reality.
(2005) In Rheumatology 44(10). p.1212-1216- Abstract
- Systemic sclerosis, scleroderma (SSc) is a disabling condition that shortens life expectancy. Disease heterogeneity and difficulties separating SSc from SSc-like conditions make classification an important issue. Limited cutaneous and diffuse cutaneous SSc, with different severity and survival, have been recognized for several years as distinct subsets. Some authors have suggested an intermediate cutaneous form with intermediate survival. This issue remains unsettled, however. The technique of capillaroscopy is helpful as an adjunct diagnostic tool to separate idiopathic Raynaud's phenomenon from SSc. Digitized video-capillaroscopy is developing as a powerful new method to assess individual capillaries over time. Using the simpler... (More)
- Systemic sclerosis, scleroderma (SSc) is a disabling condition that shortens life expectancy. Disease heterogeneity and difficulties separating SSc from SSc-like conditions make classification an important issue. Limited cutaneous and diffuse cutaneous SSc, with different severity and survival, have been recognized for several years as distinct subsets. Some authors have suggested an intermediate cutaneous form with intermediate survival. This issue remains unsettled, however. The technique of capillaroscopy is helpful as an adjunct diagnostic tool to separate idiopathic Raynaud's phenomenon from SSc. Digitized video-capillaroscopy is developing as a powerful new method to assess individual capillaries over time. Using the simpler techniques of video-capillaroscopy, different patterns have been described and named 'early', 'active', 'late' and 'slow'. The value of nailfold video-capillaroscopy to distinguish different subsets or provide prognostic information for use in daily practice remains to be assessed. The features of CREST (calcinosis, Raynaud's, oesophagus dysmotility, sclerodactyly, telangiectasias) are not confined to single subsets of SSc. There is no convincing evidence of any advantage for distinguishing the limited, intermediate and diffuse forms of SSc rather than only the limited and diffuse forms. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/138198
- author
- Wollheim, Frank LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Rheumatology
- volume
- 44
- issue
- 10
- pages
- 1212 - 1216
- publisher
- Oxford University Press
- external identifiers
-
- wos:000232103000004
- pmid:15870151
- scopus:26444614639
- ISSN
- 1462-0332
- DOI
- 10.1093/rheumatology/keh671
- language
- English
- LU publication?
- yes
- id
- b8945353-eb4d-4495-a85f-1496bac138b0 (old id 138198)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15870151&dopt=Abstract
- date added to LUP
- 2016-04-01 16:44:44
- date last changed
- 2022-03-30 17:49:29
@article{b8945353-eb4d-4495-a85f-1496bac138b0,
abstract = {{Systemic sclerosis, scleroderma (SSc) is a disabling condition that shortens life expectancy. Disease heterogeneity and difficulties separating SSc from SSc-like conditions make classification an important issue. Limited cutaneous and diffuse cutaneous SSc, with different severity and survival, have been recognized for several years as distinct subsets. Some authors have suggested an intermediate cutaneous form with intermediate survival. This issue remains unsettled, however. The technique of capillaroscopy is helpful as an adjunct diagnostic tool to separate idiopathic Raynaud's phenomenon from SSc. Digitized video-capillaroscopy is developing as a powerful new method to assess individual capillaries over time. Using the simpler techniques of video-capillaroscopy, different patterns have been described and named 'early', 'active', 'late' and 'slow'. The value of nailfold video-capillaroscopy to distinguish different subsets or provide prognostic information for use in daily practice remains to be assessed. The features of CREST (calcinosis, Raynaud's, oesophagus dysmotility, sclerodactyly, telangiectasias) are not confined to single subsets of SSc. There is no convincing evidence of any advantage for distinguishing the limited, intermediate and diffuse forms of SSc rather than only the limited and diffuse forms.}},
author = {{Wollheim, Frank}},
issn = {{1462-0332}},
language = {{eng}},
number = {{10}},
pages = {{1212--1216}},
publisher = {{Oxford University Press}},
series = {{Rheumatology}},
title = {{Classification of systemic sclerosis. Visions and reality.}},
url = {{http://dx.doi.org/10.1093/rheumatology/keh671}},
doi = {{10.1093/rheumatology/keh671}},
volume = {{44}},
year = {{2005}},
}